Zinc (picolinate vs gluconate vs bisglycinate) trials recruiting now
22 registrations that name zinc as a study arm and are recruiting or about to, as ClinicalTrials.gov listed them on Oct 20, 2026. Read each listing for its full criteria and current status.
Kymata never assesses eligibility. Each listing names its own criteria; only its study team can say whether someone can join. Trial doses are given under the trial's monitoring and are not a schedule for anyone outside it.
Filter 22 registrations
Status
Phase
5US sites across 5 states
1
2 to 4
5 to 19
20 or more
All 22 registrations
RecruitingNCT05835037
Effect of Zinc on Glucose Homeostasis
Phase 4
University of Maryland, Baltimore
About 200 people
Started Feb 16, 2024
In plain words A Phase 4 study of zinc in people 18 to 80, run by University of Maryland, Baltimore. It plans to enroll about 200 people at 1 US site.
Who it lists and where
Who the trial lists, as registered
Lists people 18 to 80. Conditions: Prediabetic State; Hyperglycemia.
Amish men or women who are 18 to 80 years old
Prediabetes (HgbA1c = 5.7-6.4% or fasting glucose levels 100-125 mg/dL)
The exclusion criteria are on the listing.
What it tests, as registered
Zinc Gluconate 30 MG; Placebo
Registered summary
The purpose of this investigation is to evaluate the impact of zinc supplementation on fasting glucose levels, hemoglobin A1c (HbA1c), and other indices of glucose homeostasis in individuals with prediabetes. The investigators hypothesize that prediabetic subjects receiving zinc will demonstrate a greater decrease in HbA1c and blood glucose compared to prediabetic subjects receiving placebo. The full summary is on the listing.
Where, as registered
1 US site in 1 state.
RecruitingNCT03908736
Thinking Zinc: a Study of Zinc Supplements on the Navajo Nation
Phase 2
University of New Mexico
About 100 people
Started May 19, 2019
In plain words A Phase 2 study of zinc in people 21 to 64, run by University of New Mexico. It plans to enroll about 100 people at 1 US site.
Who it lists and where
Who the trial lists, as registered
Lists people 21 to 64; healthy volunteers accepted. Conditions: DNA Damage; Immune System Disorder.
Men or women between the ages of 21 and 64 years of age
Lives in or near the participating communities of Blue Gap-Tachee Arizona or Red Water Pond Road Community New Mexico
Willing to provide blood and urine samples
Willing to attend study visits on scheduled dates
1 more inclusion criterion and the exclusion criteria are on the listing.
What it tests, as registered
Zinc Picolinate 15 Mg
Registered summary
This is a study to assess the effect of dietary zinc supplementation to mitigate biomarkers of metal toxicity in exposed tribal populations.
Where, as registered
1 US site in 1 state.
RecruitingNCT07405554
Zinc Supplementation With Botulinum Toxin for Overactive Bladder
Phase 2
Endeavor Health
About 72 people
Started Feb 26, 2026
In plain words A Phase 2 study of zinc in female participants 21 to 100, run by Endeavor Health. It plans to enroll about 72 people at 1 US site.
Who it lists and where
Who the trial lists, as registered
Lists female participants 21 to 100. Conditions: Overactive Bladder (OAB).
Non-pregnant adult female at least 21 years old, with no plans to become pregnant during the course of the trial) and if of child-bearing potential, with a negative pregnancy test, and if sexually active, must be using medically acceptable…
≥ 6 urgency urinary incontinence episodes on a 3-day baseline bladder diary, with these urge incontinence episodes representing greater than 50% of the total incontinent episodes recorded.
Willing and able to complete all study related items and interviews.
Refractory urgency urinary incontinence: defined as persistent symptoms despite at least one or more conservative treatments (e.g. supervised behavioral therapy, supervised physical therapy)
4 more inclusion criteria and the exclusion criteria are on the listing.
What it tests, as registered
Zinc Citrate Oral Capsule; Placebo
Registered summary
This randomized, double-blind, placebo-controlled trial evaluates whether oral zinc plus phytase supplementation modifies clinical response to intradetrusor botulinum toxin injection in patients with overactive bladder. Participants will receive either zinc plus phytase supplementation or matching placebo for five days prior to intradetrusor botulinum toxin injection. Participants will be followed for six months after treatment to assess need for repeat botulinum toxin injection, urinary symptoms, and patient-reported outcomes related to overactive bladder.
Where, as registered
1 US site in 1 state.
RecruitingNCT06567717
Zinc and Nicotinamide Riboside for Idiopathic Pulmonary Fibrosis
Phase 2
Cedars-Sinai Medical Center
About 60 people
Started Nov 3, 2025
In plain words A Phase 2 study of zinc in people 50 and older, run by Cedars-Sinai Medical Center. It plans to enroll about 60 people at 1 US site.
Who it lists and where
Who the trial lists, as registered
Lists people 50 and older. Conditions: Idiopathic Pulmonary Fibrosis.
Provision of signed and dated informed consent form
Stated willingness to comply with all study procedures and availability for the duration of the study
Be under active treatment for IPF by a local pulmonologist
Age \> 50 years
11 more inclusion criteria and the exclusion criteria are on the listing.
What it tests, as registered
Zinc; Placebos for zinc and nicotinamide riboside; Nicotinamide riboside
Registered summary
The goal of this clinical trial is to learn if a clinical trial for idiopathic pulmonary fibrosis (IPF) can recruit and retain participants from their home to study whether a combination of zinc and nicotinamide riboside can treat iIPF. The main questions are: Can the investigators recruit participants, and can participants complete study procedures without physically coming into specific clinical trial sites? Can people with IPF experience improvement in symptoms, quality of life, or functioning if they are take these supplements? The investigators will compare zinc and nicotinamide riboside… The full summary is on the listing.
Where, as registered
1 US site in 1 state.
RecruitingNCT07140874
Zinc as an Adjunctive Therapy for Cervical Dystonia
Phase 2
University of Florida
About 25 people
Starts Jun 1, 2026 (estimated)
In plain words A Phase 2 study of zinc in people 18 to 89, run by University of Florida. It plans to enroll about 25 people at 1 US site.
Who it lists and where
Who the trial lists, as registered
Lists people 18 to 89. Conditions: Cervical Dystonia.
Adults aged 18-89 years.
Diagnosed with cervical dystonia.
Receiving regular BoNT type A (Botox) injections for at least six months.
The exclusion criteria are on the listing.
What it tests, as registered
Zinc citrate; Placebo
Registered summary
The goal of this clinical trial is to evaluate if supplemental zinc can prolong the duration of benefit of botulinum toxin injections in cervical dystonia patients receiving care at the University of Florida. The main aims are: 1. To evaluate the efficacy of zinc citrate supplementation in prolonging the duration of symptom relief provided by botulinum toxin type A (Botox) injections in cervical dystonia patients. 2. To assess the safety and tolerability of zinc supplementation in this patient population. 3. The full summary is on the listing.
Where, as registered
1 US site in 1 state.
RecruitingNCT06102044
Zinc Supplementation for Young Infants With Clinical Severe Infection in Tanzania
Phase 3
Harvard School of Public Health (HSPH)
About 3,250 people
Started Dec 27, 2024
In plain words A Phase 3 study of zinc in people 0 days to 59 days, run by Harvard School of Public Health (HSPH). It plans to enroll about 3,250 people at 1 site, none in the US.
Who it lists and where
Who the trial lists, as registered
Lists people 0 days to 59 days. Conditions: Neonatal Infection.
Young infants aged 0-59 days
Diagnosis of clinical severe infection (CSI)
Ability to feed enterally
Intend to stay in the study area for 90 days
1 more inclusion criterion and the exclusion criteria are on the listing.
What it tests, as registered
Zinc Supplements; Placebo Supplements
Registered summary
Bacterial infections among young infants, including sepsis, meningitis, and pneumonia, continue to cause a substantial number of deaths globally. Zinc supplementation in combination with standard antibiotic therapy may represent a new intervention to reduce mortality and improve treatment outcomes for young infants with clinical severe infection. The Investigators will conduct a randomized, double-blind, placebo-controlled trial of zinc supplementation among young infants 0-59 days with severe clinical infection. The full summary is on the listing.
Where, as registered
No US site; Tanzania (1).
RecruitingNCT07672132
Zinc Supplementation and Inflammation in Older Medical Patients
No phase
Herlev Hospital
About 220 people
Started Jun 2, 2026
In plain words A study of zinc in people 65 and older, run by Herlev Hospital. It plans to enroll about 220 people at 1 site, none in the US.
Who it lists and where
Who the trial lists, as registered
Lists people 65 and older. Conditions: Older Medical Patients.
above 65 years old included in ZOOM out ( clinical trials no: NCT07367412)
admittet at the medical emergency department Herlev Hospital
The exclusion criteria are on the listing.
What it tests, as registered
Zinc Supplement
Registered summary
The hypothesis is that a daily supplement of 22 mg of zinc over 12 months can reduce in-flammatory biomarkers in acutely hospitalized older adults aged ≥ 65 years. The aims are to determine, in acutely hospitalized older adults aged ≥ 65 years, if a daily supplement of 22 mg of zinc over 12 months compared to control can decrease inflammato-ry biomarkers, reduce symptoms of self-reported infection, reduce readmission and mortali-ty, increase QoL, increase physical performance, investigate potential adverse events to zinc supplement, and the changes in inflammatory biomarkers. The full summary is on the listing.
Where, as registered
No US site; Denmark (1).
RecruitingNCT06151392
Effect of Probiotic and Zinc Supplementations on the Clinical Outcome in Pediatric Patients with Ventriculitis
Phase 4
Ain Shams University
About 140 people
Started Jul 1, 2023
In plain words A Phase 4 study of zinc in people 1 month to 4, run by Ain Shams University. It plans to enroll about 140 people at 1 site, none in the US.
Who it lists and where
Who the trial lists, as registered
Lists people 1 month to 4. Conditions: Ventriculitis, Infectious.
Pediatric patients admitted to neurosurgery department with the diagnosis of ventriculitis will be enrolled in the study.
The exclusion criteria are on the listing.
What it tests, as registered
Probiotic Formula; Zinc
Registered summary
The aim of the study is to evaluate the effect of non-antibiotic-based supplemental interventions in the management of ventriculitis among pediatric patients. The study objective is to detect the efficacy of probiotics and zinc when taken simultaneously with antibiotic treatment as immunomodulatory in increasing the recovery rate in pediatric population affected with ventriculitis.
Where, as registered
No US site; Egypt (1).
RecruitingNCT06219525
Higher and Standard Doses of Enteral Zinc Supplementation in Very Preterm Infants
No phase
Prince of Songkla University
About 120 people
Started Apr 2, 2024
In plain words A study of zinc in people of any age, run by Prince of Songkla University. It plans to enroll about 120 people at 1 site, none in the US.
Who it lists and where
Who the trial lists, as registered
Lists people of any age. Conditions: Very Preterm Infants; Zinc Deficiency.
Very preterm neonates (gestational age \[GA\]: 24 0/7-32 6/7 weeks and BW: 401-1800 grams) were consecutively admitted in the NICU and NMCU
Body weight at enrollment less than 800 grams
Stable neonates and full enteral feeding (150 mL/kg/day) at least for a few days
The exclusion criteria are on the listing.
What it tests, as registered
Higher dose of enteral zinc; Standard dose of enteral zinc
Registered summary
The goal of this randomized clinical trial is to compare the effect of higher (10 mg per day) versus standard (1 mg per day) doses of zinc supplementation The main questions it aims to answer are: * Growth velocities and delta z-scores during the date of start intervention until the end of the time interval (at least 2 weeks of intervention on date of 44 weeks of postmenstrual age or discharge whichever came first) in very preterm infants with a birthweight less than1800 grams. * Growth and neurodevelopment at 24 months postnatal age
Where, as registered
No US site; Thailand (1).
RecruitingNCT06612554
Zn Supplementation in HIV Immunological Non Responders
No phase
Parc de Salut Mar
About 120 people
Started Jan 2, 2025
In plain words A study of zinc in people 18 and older, run by Parc de Salut Mar. It plans to enroll about 120 people at 1 site, none in the US.
Who it lists and where
Who the trial lists, as registered
Lists people 18 and older. Conditions: HIV; Zinc Status; HIV Infection.
confirmed HIV infection;
18 years or older
Serum zinc levels less than 150ug/dl (normal range considered 75-150 ug/dl)
HIV-1 infection on stable ART for at least 3 months with cumulative ART duration of at least 6 months
2 more inclusion criteria and the exclusion criteria are on the listing.
What it tests, as registered
zinc acetate; Placebo
Registered summary
Zinc is an essential micronutrient crucial for the normal functioning of the human immune system. Zinc deficiency impairs immune function and increases infection risk, especially in vulnerable populations like people living with HIV. This project aims to study the role of zinc supplementation in improving immune response in HIV-infected individuals who are Immunological Non-Responders (INRs)-people who have not restored Cluster of differentiation 4 (CD4) T-cell counts despite receiving antiretroviral therapy (ART). The full summary is on the listing.
Where, as registered
No US site; Spain (1).
RecruitingNCT07050693
Efficacy of a 2'-Fucosylactose-based Food Supplement on the Prevention of Respiratory and Gastrointestinal Infections.
No phase
University of Bari
About 100 people
Started Apr 17, 2025
In plain words A study of zinc in people 12 months to 48 months, run by University of Bari. It plans to enroll about 100 people at 1 site, none in the US.
Who it lists and where
Who the trial lists, as registered
Lists people 12 months to 48 months. Conditions: Gastroenteric Tract; Respiratory Tract; Infections; Gastroenteric Infections.
Healthy school-going children aged 12 to 48 months who attend school at least 5 days a week
The exclusion criteria are on the listing.
What it tests, as registered
Vitamin + Zinc + micronutrient mixture; Placebo
Registered summary
Respiratory and gastrointestinal infections are frequent problems in children under 4 years of age, especially after the start of schooling. These conditions are facilitated by an incomplete maturation of the immune system and by the anatomical and functional structure of the respiratory and gastrointestinal tract still in development. Functional foods derived from the fermentation of cow's milk with probiotic strains have been proposed for the prevention of infectious diseases in children. Several products have been investigated, sometimes with conflicting results. The full summary is on the listing.
Where, as registered
No US site; Italy (1).
RecruitingNCT07193849
Zinc Oxide VS MEBO
Phase 4
King Abdullah Medical City
About 76 people
Started Dec 31, 2023
In plain words A Phase 4 study of zinc in people 18 and older, run by King Abdullah Medical City. It plans to enroll about 76 people at 2 sites, none in the US.
Who it lists and where
Who the trial lists, as registered
Lists people 18 and older. Conditions: Pressure Injury; Pressure Injury Stage 2; Bedsore; Pressure Ulcers Stage II; Pressure Ulcer, Buttock.
Willing to participate.
KAMC cases in medical ward, neuroscience ward, and intensive care unit.
Newly cases diagnosed with second stage pressure ulcer according to the European pressure ulcer advisory panel/national pressure ulcer advisory panel (NPUAP) guidelines.
The exclusion criteria are on the listing.
What it tests, as registered
MEBO Wound Ointment; zinc oxide
Registered summary
randomize control trial to evaluate the efficacy of using zinc oxide versus moist exposed wound ointment in treatment of second stage pressure ulcer.
Where, as registered
No US site; Saudi Arabia (2).
RecruitingNCT07488416
Clinical and Radiographic Outcomes of Lesion Sterilization and Tissue Repair Using Zinc Oxide/ 6-gingerol Mix Versus Triple Antibiotic Paste in Non-vital Primary Molars
No phase
Al-Azhar University
About 60 people
Started Oct 1, 2024
In plain words A study of zinc in people 4 to 8, run by Al-Azhar University. It plans to enroll about 60 people at 1 site, none in the US.
This study aims to evaluate and compare the clinical and radiographic outcomes of Lesion sterilization and tissue repair using zinc oxide/ 6-gingerol mix versus triple antibiotic paste in non-vital primary molars.
Where, as registered
No US site; Egypt (1).
RecruitingNCT07395401
Evaluation of Zinc Oxide Eugenol and Iodoform-Calcium Hydroxide as Filling Materials in Primary Molar Root Canals Prepared by Rotary and Manual Files
No phase
October University for Modern Sciences and Arts
About 44 people
Starts Feb 15, 2026 (estimated)
In plain words A study of zinc in people 5 to 8, run by October University for Modern Sciences and Arts. It plans to enroll about 44 people at 1 site, none in the US.
Who it lists and where
Who the trial lists, as registered
Lists people 5 to 8. Conditions: Carious Primary Molars Indicated for Pulpectomy.
Apparently healthy cooperative children indicated for partial pulpectomy.
Restorable primary molars.
No mobility, or external pathological root resorption.
This randomized controlled clinical trial aims to compare the clinical and radiographic outcomes of Zinc Oxide Eugenol (ZOE) and Iodoform-Calcium Hydroxide (Metapex) as root canal filling materials in primary molars prepared using either rotary or manual instrumentation techniques. Forty-four teeth from children aged 5-8 years indicated for pulpectomy will be randomly allocated into four equal groups based on the combination of instrumentation method and filling material. The full summary is on the listing.
Where, as registered
No US site; Egypt (1).
RecruitingNCT06506643
Safety and Efficacy of KLS-1 Monotherapy in Malignant Neoplasms
Phase 1 and 2
Vector Vitale LLC
About 36 people
Started May 15, 2024
In plain words A Phase 1 and 2 study of zinc in people 18 and older, run by Vector Vitale LLC. It plans to enroll about 36 people at 2 sites, none in the US.
Who it lists and where
Who the trial lists, as registered
Lists people 18 and older. Conditions: CLL; Solid Tumor, Adult.
Adult (male or female) aged ≥18 years.
Signed informed consent prior to any study-specific procedures.
Patients who are willing to make themselves available for the duration of the study and are willing to follow study procedures.
Have a performance status on the Eastern Cooperative Oncology Group (ECOG) scale of:
48 more inclusion criteria and the exclusion criteria are on the listing.
What it tests, as registered
Zinc-64 Aspartate
Registered summary
The goal of this clinical trial is to test the safety and preliminary efficacy of a new drug, KLS-1, in adults with different types of solid tumors and chronic lymphocytic leukemia (CLL). The main questions it aims to answer are: * To define Dose Limiting Toxicities (DLT) and maximum tolerated dose (MTD) of KLS-1 * To select the recommended Phase II Dose (P2D) of KLS-1 * To determine the single dose and multiple dose PK profile following IV administration of KLS-1 * What is the safest and most effective dose of KLS-1? * Does KLS-1 show anti-tumor activity in patients? * To evaluate… The full summary is on the listing.
Where, as registered
No US site; Ukraine (2).
RecruitingNCT06075134
EMG-guided Botox Injection Versus Conventional Botox Injection in Gummy Smile Patients
No phase
Cairo University
About 32 people
Started Nov 1, 2024
In plain words A study of zinc in people 18 to 50, run by Cairo University. It plans to enroll about 32 people at 1 site, none in the US.
Who it lists and where
Who the trial lists, as registered
Lists people 18 to 50; healthy volunteers accepted. Conditions: Excessive Gingival Display.
Patients with excessive gingival display.
Patients with esthetic concerns.
Patients with mild to moderate VME (vertical maxillary excess).
Normal clinical crown dimensions.
3 more inclusion criteria and the exclusion criteria are on the listing.
What it tests, as registered
Botox injection; EMG; Zinc Supplement
Registered summary
The goal of this clinical trial is to compare the effect of EMG-guided Botox injection with conventional Botox injection in Yonsei point, in patients with excessive gingival display. The main question it aims to answer is: • Does the use of electromyography (EMG) as a guide during Botox injection for patients with gummy smile has better effect than conventional injection in Yonsei point? Participants will be randomized in equal proportions between intervention and control groups. The full summary is on the listing.
Where, as registered
No US site; Egypt (1).
RecruitingNCT06854744
Zinc Oxide Ozonated Olive Oil in LSTR
No phase
Tanta University
About 30 people
Started Jan 15, 2024
In plain words A study of zinc in people 4 to 7, run by Tanta University. It plans to enroll about 30 people at 2 sites, none in the US.
Who it lists and where
Who the trial lists, as registered
Lists people 4 to 7; healthy volunteers accepted. Conditions: Pulpitis - Irreversible; Ozone; Pulp Disease, Dental; Primary Teeth.
Widening of Periodontal ligament space.
Radicular involvement.
Furcation involvement less than or equal to half of the shortest root in the vertical dimension
This study will be carried out to evaluate and compare the clinical and radiographic effect of zinc oxide-ozonated olive oil (ZnO-OO) versus Modified Triple Antibiotic Paste (MTAP) as a Lesion Sterilization and Tissue Repair Technique in Primary Molars
Where, as registered
No US site; Egypt (2).
Not yet recruitingNCT06264544
Trial to Evaluate the Efficacy of a Zinc, Selenium, and L-Tyrosine Supplement in the Prevention of Thyrotoxicosis in Subjects With r25191G/A SEPP1 Polymorphism
No phase
S.LAB (SOLOWAYS)
About 150 people
Starts Jul 30, 2025 (estimated)
In plain words A study of zinc in people 18 to 85, run by S.LAB (SOLOWAYS). It plans to enroll about 150 people at 1 site, none in the US.
Who it lists and where
Who the trial lists, as registered
Lists people 18 to 85. Conditions: Thyrotoxicosis.
Confirmed presence of one or more specified gene polymorphism r25191G/A SEPP1
TPOAb levels > 300 IU/mL
The exclusion criteria are on the listing.
What it tests, as registered
zinc, selenium, and L-tyrosine in SEPP1; Placebo
Registered summary
This randomized, double-blind, placebo-controlled trial evaluates the efficacy of a zinc, selenium, and L-tyrosine supplement in preventing thyrotoxicosis among adults aged 18-85 with elevated TPOAb levels and the r25191G/A SEPP1 polymorphism. The study excludes those with thyroid disease, pregnant/breastfeeding women, and individuals allergic to the supplement. Key endpoints include changes in thyroid antibodies and hormones over a 6-month period. The full summary is on the listing.
Where, as registered
No US site; Russia (1).
Not yet recruitingNCT07424053
Effect of Graphene Oxide on Vital and Non-Vital Primary Teeth Compared to the Conventional Techniques
No phase
Al-Azhar University
About 126 people
Starts Apr 2026 (estimated)
In plain words A study of zinc in people 5 to 10, run by Al-Azhar University. It plans to enroll about 126 people and lists no sites yet.
Who it lists and where
Who the trial lists, as registered
Lists people 5 to 10. Conditions: Primary Teeth Indicated for Pulp Therapy.
Cooperative child
Presence of symptom-free deep carious lesions
Presence of at least two-thirds of the root length radiographically; restorable tooth (Second Arm)
Primary teeth diagnosed with pulp necrosis, root resorption equal to or less than one-third (with sufficient dental structure for absolute isolation with rubber dam)
10 more inclusion criteria and the exclusion criteria are on the listing.
What it tests, as registered
Graphene Oxide using vital pulpotomy technique; MTA using vital pulpotomy technique; Zinc Oxide and Eugenol using vital pulpotomy technique; Graphene Oxide using non-vital pulpotomy technique; LSTR using non-vital pulpotomy technique; Zinc Oxide and Eugenol using non-vital pulpotomy
Registered summary
The null hypothesis of the current study suggested that there will be no significant difference regarding the effect of Graphene Oxide (GO), Lesion sterilization and tissue repair (LSTR) and Zinc Oxide and Eugenol on the clinical and radiographic success rate of non-vital pulpotomy of primary teeth and that there will be no significant difference regarding the effect of Graphene Oxide (GO), MTA and Zinc Oxide and Eugenol on the clinical and radiographic success rate of vital pulpotomy of primary teeth. The full summary is on the listing.
Where, as registered
No sites listed yet.
Not yet recruitingNCT06807996
Effects of Zinc Supplementation on Patients With Elevated Glycemic Status
No phase
Zhilei Shan
About 124 people
Starts Jul 1, 2025 (estimated)
In plain words A study of zinc in people 18 and older, run by Zhilei Shan. It plans to enroll about 124 people and lists no sites yet.
Who it lists and where
Who the trial lists, as registered
Lists people 18 and older. Conditions: Elevated Blood Glucose.
Fasting blood glucose ≥ 6.1 mmol /L;
HBA1c ≥ 5.7%;
OGTT 2-hour or postprandial blood glucose ≥ 7.8 mmol/L;
Patients with previously diagnosed type 2 diabetes with stable drug hypoglycemic treatment and blood glucose controlled well.
The goal of this randomized, double-blind, placebo-controlled study included patients with elevated glycemic status is to investigate whether zinc supplementation (4mg per day) has beneficial effects on controlling blood glucose.
Where, as registered
No sites listed yet.
Not yet recruitingNCT06664008
The Effect of Probiotic and Zinc Supplementation in Patients With Gastroesophageal Reflux Disease
Phase 4
Ain Shams University
About 120 people
Starts Nov 1, 2024 (estimated)
In plain words A Phase 4 study of zinc in people 18 to 74, run by Ain Shams University. It plans to enroll about 120 people and lists no sites yet.
Who it lists and where
Who the trial lists, as registered
Lists people 18 to 74. Conditions: Gastro-oesophageal Reflux Disease.
Adults aged 18-74 years; (both male and female).
Esophagitis that might be confirmed by gastroscopy.
Patients with confirmed symptoms of GERD N.B.: The typical clinical presentation of GERD is heartburn and regurgitation.
The exclusion criteria are on the listing.
What it tests, as registered
PPI (proton pump inhibitor); Probiotic; Zinc
Registered summary
Introduction: Gastroesophageal reflux disease (GERD) is a common digestive disorder affecting the esophagus and gastro-duodenum, presenting symptoms such as acid reflux and heartburn. GERD\'s incidence, symptoms, and prognosis are heavily influenced by diet and lifestyle factors. Current management of GERD involves lifestyle modifications (e.g., weight loss, dietary changes) and pharmacologic agents like proton pump inhibitors (PPIs), histamine-2-receptor blockers (H2 B), antacids, and medications that affect gastrointestinal motility (Kröner et al., 2021). The full summary is on the listing.
Where, as registered
No sites listed yet.
Not yet recruitingNCT07265089
Zinc Oxide-Ozonated Olive Oil vs Metapex in Primary Anterior Teeth
No phase
Cairo University
About 52 people
Starts Dec 1, 2025 (estimated)
In plain words A study of zinc in people 3 to 5, run by Cairo University. It plans to enroll about 52 people at 1 site, none in the US.
Who it lists and where
Who the trial lists, as registered
Lists people 3 to 5; healthy volunteers accepted. Conditions: Carious Anterior Teeth.
Children aged 3-5 years.
Primary anterior teeth requiring root canal treatment due to irreversible pulpitis.
Cooperative behavior child.
Parents provided written informed consent. -
The exclusion criteria are on the listing.
What it tests, as registered
Zinc Oxide-Ozonated Olive Oil; Metapex
Registered summary
This randomized clinical trial compares zinc oxide-ozonated olive oil and Metapex as root canal filling materials in primary anterior teeth of children aged 3-5 years. The study aims to evaluate their clinical and radiographic success over 12 months.Clinical evaluation includes pain, swelling, and mobility; radiographic evaluation includes periapical healing and resorption.