Xanthohumol trials recruiting now

4 registrations that name xanthohumol as a study arm and are recruiting or about to, as ClinicalTrials.gov listed them on Oct 20, 2026. Read each listing for its full criteria and current status.

Kymata never assesses eligibility. Each listing names its own criteria; only its study team can say whether someone can join. Trial doses are given under the trial's monitoring and are not a schedule for anyone outside it.

Filter 4 registrations

Status

Phase

All 4 registrations

RecruitingNCT06286657

Xanthohumol and Viral Infections (XL)

  • No phase
  • University of Vienna
  • About 100 people
  • Started Aug 1, 2023

In plain words A study of xanthohumol in people 18 to 70, run by University of Vienna. It plans to enroll about 100 people at 1 site, none in the US.

Who it lists and where

Who the trial lists, as registered

Lists people 18 to 70; healthy volunteers accepted. Conditions: Infection Viral.

  • healthy
  • BMI >18 kg/m² or < 28kg/m²

The exclusion criteria are on the listing.

What it tests, as registered

Xanthohumol; Placebo

Registered summary

The aim of the present study is to determine if a regular oral supplementation of xanthohumol attenuate the severity of symptoms and duration of´viral infections.

Where, as registered

No US site; Austria (1).

RecruitingNCT06225258

Xanthohumol as an Adjuvant in the Treatment of Septic Shock

  • Phase 2
  • Medical University of Lublin
  • About 50 people
  • Started Jan 9, 2023

In plain words A Phase 2 study of xanthohumol in people 18 and older, run by Medical University of Lublin. It plans to enroll about 50 people at 1 site, none in the US.

Who it lists and where

Who the trial lists, as registered

Lists people 18 and older. Conditions: Septic Shock; Pneumonia; ARDS.

  • a septic shock in the early, acute phase,
  • respiratory insufficiency required mechanical ventilation with PaO2/FiO2 < 150,
  • bacterial infection,
  • procalcitonin higher than 5 ng/mL and interleukin 6 higher than 100 pg/mL,

2 more inclusion criteria and the exclusion criteria are on the listing.

What it tests, as registered

Xanthohumol

Registered summary

Septic shock (SS) is a life-threatening condition resulting from excessive inflammatory response to bacterial, viral or/and fungal infections. It is associated with dysregulation of the immune system, activation of immune cells, and massive release of cytokines, commonly known as the cytokine storm (CS). The clinical manifestations of SS depend on the initial site of infection. However, the classic symptoms are associated with severe dysfunction of the respiratory and cardiovascular systems, which are observed from the early phase. The full summary is on the listing.

Where, as registered

No US site; Poland (1).

RecruitingNCT06745102

Hop Compounds on the Immune System in Overweight People

  • No phase
  • University of Vienna
  • About 24 people
  • Started Feb 1, 2024

In plain words A study of xanthohumol in people 18 to 75, run by University of Vienna. It plans to enroll about 24 people at 1 site, none in the US.

Who it lists and where

Who the trial lists, as registered

Lists people 18 to 75. Conditions: Inflammatory Response.

  • BMI 25 - 29,9 kg/m² as well as one or more of the following incipient metabolic diseases:
  • pre-diabetes (fasting blood glucose 100-125 mg/dL),
  • fatty liver (grade 1-3),
  • high-normal blood pressure to mild hypertension (grade 1, systolic 140-159 mmHg)

The exclusion criteria are on the listing.

What it tests, as registered

Xanthohumol; Iso-alpha Acids; Xanthohumol + Iso-alpha Acids

Registered summary

The aim of the present study is to determine the effect of Iso-alpha Acids and Xanthohumol from hops on the immune response in overweight participants.

Where, as registered

No US site; Austria (1).

RecruitingNCT06286644

Hop Compounds on the Immune System (VH)

  • No phase
  • University of Vienna
  • About 14 people
  • Started May 30, 2022

In plain words A study of xanthohumol in people 18 to 70, run by University of Vienna. It plans to enroll about 14 people at 1 site, none in the US.

Who it lists and where

Who the trial lists, as registered

Lists people 18 to 70; healthy volunteers accepted. Conditions: Inflammatory Response.

  • healthy
  • BMI: >18,5 kg/m² or <30 kg/m²

The exclusion criteria are on the listing.

What it tests, as registered

Xanthohumol; Iso-alpha-Acids; Xanthohumol + Iso-alpha-Acids

Registered summary

The aim of the present study is to determine the effect of Iso-alpha-Acids and Xanthohumol from hops on the immune response of healthy participants over a timeframe of 6 hours.

Where, as registered

No US site; Austria (1).

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