Whey protein (and other protein powders) trials recruiting now
40 registrations that name whey protein as a study arm and are recruiting or about to, as ClinicalTrials.gov listed them on Oct 20, 2026. Read each listing for its full criteria and current status.
Kymata never assesses eligibility. Each listing names its own criteria; only its study team can say whether someone can join. Trial doses are given under the trial's monitoring and are not a schedule for anyone outside it.
Filter 40 registrations
Status
Phase
10US sites across 4 states
1
2 to 4
5 to 19
20 or more
All 40 registrations
RecruitingNCT07704476
EXERT-BC Protein: Protein Supplementation to Improve Body Composition After Treatment for Breast Cancer
No phase
Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)
About 40 people
Started Jun 18, 2026
In plain words A study of whey protein in female participants 20 to 89, run by Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute). It plans to enroll about 40 people at 2 US sites.
Who it lists and where
Who the trial lists, as registered
Lists female participants 20 to 89. Conditions: Cancer; Breast Cancer.
Age 20-89 years
Women prescribed exercise as a SOC
Women with a biopsy proven diagnosis of ductal carcinoma in situ (DCIS) or invasive carcinoma of the breast
Women must have undergone treatment for breast cancer, including one or more of the following: surgery, radiation therapy, chemotherapy, immunotherapy, or hormonal therapy. Women undergoing active chemotherapy are not allowed on study.
2 more inclusion criteria and the exclusion criteria are on the listing.
What it tests, as registered
Whey protein (60 grams); No protein
Registered summary
In this study, the investigators hypothesize that a high dose of post-workout protein after each exercise session will have greater improvements in changes in body composition, including muscle mass and percent body fat versus a workout alone.
Where, as registered
2 US sites in 1 state.
RecruitingNCT06311058
Protein Supplementation After ACL Surgery
No phase
The Methodist Hospital Research Institute
About 102 people
Started Feb 16, 2024
In plain words A study of whey protein in people 16 to 40, run by The Methodist Hospital Research Institute. It plans to enroll about 102 people at 1 US site.
Who it lists and where
Who the trial lists, as registered
Lists people 16 to 40. Conditions: ACL Reconstruction.
Subjects will include patients age 16 to 40 undergoing primary ACL reconstruction for an acute ACL tear with the PI or Sub-investigators
The exclusion criteria are on the listing.
What it tests, as registered
Whey protein isolate; Protein + BAA; Placebo
Registered summary
The purpose of the study is to assess the longitudinal post-operative care effects of protein supplementation on muscle atrophy in the post-operative period following ACL reconstruction. The main outcome will be muscle size/mass as measured using dual energy x-ray absorptiometry (DEXA) scanning. The primary objective is to assess for any beneficial impact of protein supplementation, with implications of standardizing a recommended protocol for protein supplementation after ACL reconstruction. The full summary is on the listing.
Where, as registered
1 US site in 1 state.
RecruitingNCT06628349
Prandial Metabolic Phenotyping in Sarcopenic Older Adults Comparing Plant Based and Whey Based Protein
No phase
Texas A&M University
About 100 people
Started Feb 1, 2024
In plain words A study of whey protein in people 50 to 95, run by Texas A&M University. It plans to enroll about 100 people at 1 US site.
Who it lists and where
Who the trial lists, as registered
Lists people 50 to 95; healthy volunteers accepted. Conditions: Protein Metabolism.
Age 50-95 years old
Diagnosis of Chronic Obstructive Pulmonary Disease (COPD); COPD group only
Stable body-weight (±5%) for the past 3 months
Ability to walk, sit down, and stand up (independently or with walking assistance device)
2 more inclusion criteria and the exclusion criteria are on the listing.
What it tests, as registered
Whey Protein Isolate 90%; Soy Protein Isolate (90% Protein); Organic Pea Protein Isolate; Placebo (Water)
Registered summary
The researchers overall objective is to determine whether plant and animal protein based proteins affect the anabolic responses across aging populations differently due to specific changes in the essential amino acids (EAA) and non-essential amino acids (NEAA) kinetic responses. The researchers central hypothesis is that a high EAA to NEAA ratio in a protein meal is related to higher anabolic response to the meal. The researchers also hypothesize that the type of NEAA in a protein meal also affects the anabolic capacity of the meal. The full summary is on the listing.
Where, as registered
1 US site in 1 state.
RecruitingNCT07029243
Prehab and Creatine/Whey Supplementation in Frailty Among Patients With Cirrhosis
No phase
University of California, San Francisco
About 100 people
Started Apr 15, 2026
In plain words A study of whey protein in people 18 and older, run by University of California, San Francisco. It plans to enroll about 100 people at 1 US site.
Who it lists and where
Who the trial lists, as registered
Lists people 18 and older. Conditions: Cirrhosis; Frailty; Sarcopenia.
Confirmed diagnosis of cirrhosis by ICD-10 code, liver biopsy, abdominal imaging, or transient elastography
Access to digital device and internet at home
Ability to provide written informed consent before any study-related activities
Ability to remain in study for at least 3 months
The exclusion criteria are on the listing.
What it tests, as registered
HEAL-ME digital app; Creatine supplementation; Whey protein supplementation; Placebo
Registered summary
Frailty and muscle health are important for patients with chronic liver disease. This study looks at the use of a digital prehabilitation app (HEAL-ME) plus creatine and whey protein combination supplementation on maintaining muscle health in patients with liver disease. The investigators anticipate that this combination of supplementation and nutrition/exercise prehabilitation app will maintain muscle health in patients with liver disease.
Where, as registered
1 US site in 1 state.
RecruitingNCT04949451
Time Restricted Feeding, Muscle, and Metabolism
No phase
University of Arkansas, Fayetteville
About 90 people
Started Jun 13, 2021
In plain words A study of whey protein in people 25 to 50, run by University of Arkansas, Fayetteville. It plans to enroll about 90 people at 1 US site.
Who it lists and where
Who the trial lists, as registered
Lists people 25 to 50; healthy volunteers accepted. Conditions: Overweight; Obesity.
Resides in Northwest Arkansas
Age 25-50 years
BMI > 25
All ethnicities
1 more inclusion criterion and the exclusion criteria are on the listing.
What it tests, as registered
Whey protein supplement; Ketogenic aid; Control group - time restricted feeding only
Registered summary
Effective nutrition strategies for combatting and/or preventing obesity still need to be identified. This has been the case despite the numerous and different approaches that have been taken. Potential targets for combatting/preventing obesity have been identified, but long-term solutions have not emerged. This study uses time restricted feeding to study the role of dietary protein in obesity prevention and/or treatment. The full summary is on the listing.
Where, as registered
1 US site in 1 state.
RecruitingNCT07806838
Effects of Dietary Supplements on Muscle Mass and Function While Using GLP-1 Medication
No phase
University of California, Los Angeles
About 75 people
Starts Sep 10, 2026 (estimated)
In plain words A study of whey protein in people 18 and older, run by University of California, Los Angeles. It plans to enroll about 75 people at 1 US site.
Who it lists and where
Who the trial lists, as registered
Lists people 18 and older; healthy volunteers accepted. Conditions: Obesity & Overweight; Muscle Mass and Strength; Muscle Function.
Male or female ≥18 years of age at screening visit.
BMI >27 kg/m² with weight-related conditions OR BMI >30 kg/m².
Taking any FDA-approved GLP-1 medication, daily oral or weekly injectable, started up to three months ago, and experiencing at least 1 lb of weight loss per week.
Screening laboratory tests without significant abnormalities that might interfere with the study.
The exclusion criteria are on the listing.
What it tests, as registered
Whey Protein Supplementation; Maltodextrin Placebo Capsules; Mixed Spice Capsules
Registered summary
This pilot study will examine whether daily protein supplementation with or without a mixture of culinary spices can help preserve muscle mass and function in adults who are using GLP-1 medications for weight management. The study will include 75 adults who recently started a GLP-1 medication and are experiencing weight loss. Participants will be randomly assigned to one of three groups: standard of care, protein supplementation plus placebo capsules, or protein supplementation plus mixed spice capsules. The study will last 6 months. The full summary is on the listing.
Where, as registered
1 US site in 1 state.
RecruitingNCT06694155
Whey Protein Ingestion and Glucose Control in Pre- and Post Diabetic Individuals
No phase
University of Arkansas
About 40 people
Started Jan 15, 2025
In plain words A study of whey protein in people 50 to 70, run by University of Arkansas. It plans to enroll about 40 people at 1 US site.
Who it lists and where
Who the trial lists, as registered
Lists people 50 to 70. Conditions: Prediabetes / Type 2 Diabetes.
Males and females ages 50-70 years.
Body mass index between 25-45 kg/m2
Capable of providing informed consent.
COVID-19 negative and/or asymptomatic.
2 more inclusion criteria and the exclusion criteria are on the listing.
What it tests, as registered
Whey Protein Isolate Crossover; Placebo
Registered summary
To examine the effects of twice daily whey protein consumption on blood glucose and insulin in pre-diabetic and diabetic individuals
Where, as registered
1 US site in 1 state.
RecruitingNCT06858449
Resistance Training and Post Workout Protein to Improve Body Composition During Neoadjuvant Chemotherapy for Breast Cancer
No phase
Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)
About 30 people
Started Jan 2, 2025
In plain words A study of whey protein in female participants 20 to 89, run by Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute). It plans to enroll about 30 people at 1 US site.
Who it lists and where
Who the trial lists, as registered
Lists female participants 20 to 89. Conditions: Cancer; Breast Cancer.
Age 20-89 years
Women with a biopsy proven diagnosis of invasive carcinoma of the breast.
Women must undergo neoadjuvant chemotherapy for breast cancer treatment prior to surgery
Must be able to read and understand English and consent for themselves.
The exclusion criteria are on the listing.
What it tests, as registered
Whey protein (20 grams); Whey protein (60 grams)
Registered summary
In this study, the investigators hypothesize that a high dose of post-workout protein nutrition regimen focused on food quality and an observed exercise regimen utilizing high-load resistance training initiated during or after cancer treatment will improve body composition and functional capacity.
Where, as registered
1 US site in 1 state.
RecruitingNCT06537115
Clinical Intervention of Idecalcitol Combined With Whey Protein Powder and Exercise for Sarcopenia
Phase 4
Zhejiang Provincial People's Hospital
About 450 people
Started Jun 16, 2024
In plain words A Phase 4 study of whey protein in people 30 and older, run by Zhejiang Provincial People's Hospital. It plans to enroll about 450 people at 5 sites, none in the US.
Who it lists and where
Who the trial lists, as registered
Lists people 30 and older. Conditions: Sarcopenia.
Age 30 or above;
Meeting the diagnostic criteria for sarcopenia according to the definition of AWGS; ③ Able to walk, willing to accept a comprehensive intervention plan, and guarantee to complete the treatment course; ④ Both patients and their families…
The exclusion criteria are on the listing.
What it tests, as registered
exercise; whey protein powder; Eldecalcitol
Registered summary
This clinical trial is a multicenter, single-blind, prospective, randomized controlled clinical application study. Subjects who met the trial criteria and signed the informed consent form were randomly divided into a control group, an experimental group 1, and an experimental group 2. The full summary is on the listing.
Where, as registered
No US site; China (5).
RecruitingNCT06825377
Comparing High-protein Vs. Standard Protein Nutritional Support in Critically Ill Patients At Risk for Refeeding Syndrome
No phase
Shahid Beheshti University
About 150 people
Started Feb 13, 2025
In plain words A study of whey protein in people 18 to 65, run by Shahid Beheshti University. It plans to enroll about 150 people at 1 site, none in the US.
Who it lists and where
Who the trial lists, as registered
Lists people 18 to 65. Conditions: Critical Illness; Malnutrition; Refeeding Syndrome; At Risk for Refeeding Syndrome.
Willingness to cooperate and complete the informed consent form by the patient or legal guardian;
age ≤ 18 years and < 65 years;
Non-pregnant and non-lactating;
Serum creatinine ≥ 1.1 mg/dl for women and ≥ 1.2 mg/dl for men;
9 more inclusion criteria and the exclusion criteria are on the listing.
What it tests, as registered
Whey protein
Registered summary
The goal of this clinical trial is to determine the optimal protein administration strategy for enhancing both nutritional and clinical outcomes, as well as reducing complications and mortality in ICU patients at risk for refeeding syndrome (RS). This study will include critically ill patients at risk for RS who are receiving supportive nutrition. The primary hypothesis is that higher protein intake will lead to a decreased incidence of refeeding syndrome. The full summary is on the listing.
Where, as registered
No US site; Iran (1).
RecruitingNCT04883515
Effects of Oral Glutamine Supplementation on Insulin Resistance and Functional Intestinal Disorders in Obese Patients.
No phase
University Hospital, Rouen
About 110 people
Started Mar 1, 2023
In plain words A study of whey protein in people 18 to 65, run by University Hospital, Rouen. It plans to enroll about 110 people at 1 site, none in the US.
Who it lists and where
Who the trial lists, as registered
Lists people 18 to 65. Conditions: Obesity; Insulin Resistance.
Patients aged from 18 to 65 years
Patient with h grade II or III obesity (body mass index equal or higher than 35 kg/m2)
Patient with insulino-resistance (fasting glycaemia ≥ 1g/l et < 1.26 g/l)
Patient with irritable bowel syndrome (Rome IV criteria ≥ 2)
Obesity, which has a prevalence at 15% in France, is a major public health concern. Altered glycemic control and irritable bowel syndrome (IBS) are frequently observed in obese patients and lead to reduce the quality of life. In the last decades, the role of gut microbiota and intestinal permeability has been underlined in obesity, glycemic control and IBS. Interestingly, experimental and clinical data show that glutamine, an amino acid, is able to maintain or restore intestinal permeability in different conditions. The full summary is on the listing.
Where, as registered
No US site; France (1).
RecruitingNCT06573749
Effect of 12-week Milk Fat Globule Membrane Supplementation on the Human Muscle Function of Healthy, Recreationally Active Adults
No phase
Loughborough University
About 96 people
Started Mar 28, 2025
In plain words A study of whey protein in people 18 to 75, run by Loughborough University. It plans to enroll about 96 people at 1 site, none in the US.
Who it lists and where
Who the trial lists, as registered
Lists people 18 to 75; healthy volunteers accepted. Conditions: Ageing Well; Neuromuscular Function.
18-30 or 60-75 years old
Male or female
Healthy with no contraindications to exercise
Classified as recreationally active (meet the government's guidelines for weekly physical activity - 150 minutes of moderate physical activity or 75 minutes of vigorous physical activity)
The exclusion criteria are on the listing.
What it tests, as registered
Bioactive whey protein concentrate; Whey protein isolate supplement
Registered summary
The main aim of this study is to understand if chronic supplementation (12 weeks) of a milk fat globule membrane containing supplement, called bioactive whey protein concentrate, improves human muscle function greater than a placebo supplement within a cohort of healthy, recreationally active adults. Furthermore, we aim to investigate whether any potential benefits of milk fat globule membrane are influenced by age through the assessment of 2 distinct age subgroups (young and older). The full summary is on the listing.
Where, as registered
No US site; United Kingdom (1).
RecruitingNCT06821802
Protein Supplementation in Hyponatremia Due to the Syndrome of Inappropriate Antidiuresis
No phase
University Hospital, Basel, Switzerland
About 70 people
Started Apr 14, 2025
In plain words A study of whey protein in people 18 and older, run by University Hospital, Basel, Switzerland. It plans to enroll about 70 people at 1 site, none in the US.
Who it lists and where
Who the trial lists, as registered
Lists people 18 and older. Conditions: Hyponatremia; Syndrome of Inappropriate Antidiuresis.
Adult patients with confirmed SIAD during the hospital stay or at screening, defined by:
Plasma sodium concentration <135 mmol/L
Plasma osmolality <300 mOsm/kg
Urine osmolality >100 mOsm/kg
2 more inclusion criteria and the exclusion criteria are on the listing.
What it tests, as registered
Moltein PURE Protein Powder; Fluid restriction
Registered summary
The goal of this study is to assess the impact of protein supplementation on hyponatremia caused by the syndrome of inappropriate antidiuresis during hospitalization.
Where, as registered
No US site; Switzerland (1).
RecruitingNCT06291038
Efficacy of Glutamine Supplementation in Patients Suffering From Irritable Bowel Syndrome With Impaired Intestinal Permeability
No phase
University Hospital, Rouen
About 60 people
Started Oct 3, 2024
In plain words A study of whey protein in people 18 to 75, run by University Hospital, Rouen. It plans to enroll about 60 people at 4 sites, none in the US.
Who it lists and where
Who the trial lists, as registered
Lists people 18 to 75. Conditions: Irritable Bowel Syndrome.
Adult aged 18 to 75
Diarrheal irritable bowel syndrome (IBS-D), according to the Rome IV criteria (appendix 2)
Francis score > 175/500 at inclusion (corresponding to moderate to severe IBS)
Treatments for IBS stable for >1 month
4 more inclusion criteria and the exclusion criteria are on the listing.
What it tests, as registered
• Experimental group: treatment with glutamine at a dose of 5g 3 times a day for 8 weeks; • Control group: treatment with a protein powder (Protifar) (Placébo) 5g 3 times a day for 8 weeks.
Registered summary
Irritable bowel syndrome (IBS) affects approximately 5% of the general population and remains a daily problem in the practice of clinicians with inconsistent effectiveness of treatments while patients' expectations are high. One of the functional abnormalities described during IBS is increased intestinal permeability. This increase in intestinal permeability is primarily present in the diarrheal subtype (IBS-D) and can be measured using the lactulose/mannitol test. The full summary is on the listing.
Where, as registered
No US site; France (4).
RecruitingNCT07594444
Whey Protein and Adaptogenic Supplementation in Physically Active Females
No phase
Sports Performance and Applied Research in Trials and Analysis
About 60 people
Started Jul 1, 2026
In plain words A study of whey protein in female participants 18 to 45, run by Sports Performance and Applied Research in Trials and Analysis. It plans to enroll about 60 people at 1 site, none in the US.
Currently participating in regular structured athletic or physical training (≥3 sessions per week)
Free from musculoskeletal injury that would prevent testing
Willing to maintain usual diet and training habits during the study
1 more inclusion criterion and the exclusion criteria are on the listing.
What it tests, as registered
Whey protein; Whey Protein With Adaptogenic Blend; Plant Protein Supplement; Plant Protein With Adaptogenic Blend
Registered summary
The goal of this clinical trial is to learn whether whey protein or plant protein supplements, with or without an adaptogenic herb blend, can improve strength, recovery, stress, and wellbeing in active females. The adaptogenic blend contains ashwagandha root extract and shatavari root extract. The full summary is on the listing.
Where, as registered
No US site; United Kingdom (1).
RecruitingNCT07716904
Whey Protein and Adaptogenic Supplementation in Physically Active Males
No phase
Sports Performance and Applied Research in Trials and Analysis
About 60 people
Started Jul 20, 2026
In plain words A study of whey protein in male participants 18 to 45, run by Sports Performance and Applied Research in Trials and Analysis. It plans to enroll about 60 people at 1 site, none in the US.
Who it lists and where
Who the trial lists, as registered
Lists male participants 18 to 45; healthy volunteers accepted. Conditions: Sports Nutritional Sciences; Sports Nutrition; Recovery; Recovery Following Exercise; Muscle Strength Recovery.
Male, aged 18-45 years
Currently participating in regular structured athletic or physical training (≥3 sessions per week)
Free from musculoskeletal injury that would prevent testing
Willing to maintain usual diet and training habits during the study
2 more inclusion criteria and the exclusion criteria are on the listing.
What it tests, as registered
Whey protein; Dietary Supplement: Whey Protein With Adaptogenic Blend
Registered summary
The goal of this clinical trial is to learn whether whey protein, with or without an adaptogenic herb blend, can improve strength, recovery, stress, and wellbeing in active males. The adaptogenic blend contains 600mg ashwagandha root extract.The main questions the study aims to answer are: Does whey protein improve muscle strength and recovery in physically active males? Does adding ashwagandha to whey protein further improve stress, recovery, sleep, and wellbeing compared with protein alone? Are there differences between whey protein when combined with the adaptogenic blend? Researchers will… The full summary is on the listing.
Where, as registered
No US site; United Kingdom (1).
RecruitingNCT07299110
Effect of Whey Protein Versus Egg Albumen Protein Challenge on Blood Ammonia Level in Patients of Decompensated Ethanol Related Cirrhosis.
No phase
Institute of Liver and Biliary Sciences, India
About 50 people
Starts Dec 12, 2025 (estimated)
In plain words A study of whey protein in people 18 to 70, run by Institute of Liver and Biliary Sciences, India. It plans to enroll about 50 people at 1 site, none in the US.
Who it lists and where
Who the trial lists, as registered
Lists people 18 to 70. Conditions: Decompensated Cirrhosis Ethanol Related.
Known or newly diagnosed (clinical, imaging) case of decompensated ethanol related cirrhosis patients.
Age (18-70 years).
Informed consent to participate in the study.
The exclusion criteria are on the listing.
What it tests, as registered
Whey Protein; Egg Albumen
Registered summary
In cirrhosis, altered nitrogen metabolism and reduced hepatic clearance of ammonia contribute to the development of Minimal Hepatic Encephalopathy (MHE)-a subclinical but functionally debilitating condition. While adequate protein intake is essential to prevent sarcopenia in cirrhotic patients, the type of protein consumed can significantly influence postprandial ammonia generation, thereby affecting neurocognitive status. The full summary is on the listing.
Where, as registered
No US site; India (1).
RecruitingNCT05922462
Effects of Increased Greek Yogurt Consumption in Youth and Young Adult Athletes
No phase
Brock University
About 40 people
Started Sep 1, 2023
In plain words A study of whey protein in people 15 to 22, run by Brock University. It plans to enroll about 40 people at 1 site, none in the US.
Who it lists and where
Who the trial lists, as registered
Lists people 15 to 22; healthy volunteers accepted. Conditions: Bone Growth Abnormal; Inflammation.
Competitive youth or varsity athletes
The exclusion criteria are on the listing.
What it tests, as registered
Greek yogurt; Whey protein
Registered summary
Physical activity and dairy consumption during growth and development are each known to improve peak bone mass in young adults. Peak bone mass, the maximum amount of bone a person will have in their lifetime, is typically reached in the early 20's in females and late 20's in males. However, evidence suggests that young people do not consume enough dairy to maximize their bone mass. The resulting effect in peak bone mass can be troublesome, particularly for athletes, such as volleyball players. The full summary is on the listing.
Where, as registered
No US site; Canada (1).
RecruitingNCT07303543
Preventing Muscle Loss After Bariatric Surgery: Protein-Collagen Supplementation and Resistance Exercise
No phase
Medipol University
About 35 people
Started Aug 2, 2022
In plain words A study of whey protein in people 20 to 50, run by Medipol University. It plans to enroll about 35 people at 1 site, none in the US.
Who it lists and where
Who the trial lists, as registered
Lists people 20 to 50. Conditions: Bariatric Surgery; Muscle Loss.
Being between 20-50 years old
Body mass index; 35 ≤ BMI< 60 kg/m2
Not being pregnant
Not being addicted to alcohol and drugs
2 more inclusion criteria and the exclusion criteria are on the listing.
What it tests, as registered
Whey protein supplement; Hydrolyzed Collagen Supplement; Vitamin and Mineral Supplementation; Resistance Exercise Program
Registered summary
The aim of this clinical trial is to investigate the effectiveness of collagen, considered a new approach to prevent muscle mass loss after bariatric surgery, and to demonstrate the relationship between this effect and exercise. The key questions it aims to answer are: Does whey protein supplementation with collagen combined with resistance exercise prevent muscle mass loss after bariatric surgery? Do whey protein supplementation with collagen combined with resistance exercise affect fat mass after bariatric surgery? Researchers will compare collagen with whey protein. The full summary is on the listing.
Where, as registered
No US site; Turkey (Türkiye) (1).
RecruitingNCT07285811
GLycaemic Outcomes With Whey Protein in ageING
No phase
University of Birmingham
About 32 people
Started Jan 2, 2026
In plain words A study of whey protein in people 70 to 90, run by University of Birmingham. It plans to enroll about 32 people at 2 sites, none in the US.
Who it lists and where
Who the trial lists, as registered
Lists people 70 to 90; healthy volunteers accepted. Conditions: Type 2 Diabetes.
Male or female
70-90 years old
Type 2 Diabetes (confirmed with glycated haemoglobin (HbA1c) >6.5% in clinic or in SportExR)
Stable body mass (body mass index (BMI) ≤40kg/m2)
5 more inclusion criteria and the exclusion criteria are on the listing.
What it tests, as registered
Glycaemic control with whey protein; Glycaemic control with different doses of whey protein
Registered summary
The goal of this placebo-controlled, partial crossover design study is to identify the impact of consuming whey protein before meals on free-living glucose control in older adults living with type 2 diabetes. The primary specific objective is to determine the effect of a thrice daily whey protein pre-meal supplementation at two doses, on glucose excursions over a 7-day free-living period in adults aged 70-90 years of age, living with type 2 diabetes, compared with a non-protein placebo. Participants will consume the whey protein and placebo for 7 days each, before each meal. The full summary is on the listing.
Where, as registered
No US site; United Kingdom (2).
RecruitingNCT04869098
Effects of an Evening PROtein PrEload on Metabolic Health in Night ShIfT Workers (PROPENSITy)
No phase
University of Adelaide
About 30 people
Started Apr 27, 2021
In plain words A study of whey protein in female participants 35 to 65, run by University of Adelaide. It plans to enroll about 30 people at 1 site, none in the US.
Who it lists and where
Who the trial lists, as registered
Lists female participants 35 to 65; healthy volunteers accepted. Conditions: Type 2 Diabetes; Shift-work Disorder.
Female
Night shift workers (with a minimum of 6 months in their current shift work schedule)
35-65 years
BMI 28.0-35.0 kg/m2; waist circumference > 80cm
1 more inclusion criterion and the exclusion criteria are on the listing.
What it tests, as registered
whey protein; Placebo
Registered summary
This study will compare the effects of a whey protein supplement or a placebo consumed before the evening meal on health outcomes in night shift workers.
Where, as registered
No US site; Australia (1).
RecruitingNCT06367413
Effects of Protein and NAC Co-ingestion on Skeletal Muscle Recovery
No phase
University of Thessaly
About 30 people
Started Apr 8, 2024
In plain words A study of whey protein in male participants 18 to 27, run by University of Thessaly. It plans to enroll about 30 people at 1 site, none in the US.
Who it lists and where
Who the trial lists, as registered
Lists male participants 18 to 27; healthy volunteers accepted. Conditions: Aseptic Muscle Injury.
Free of asthma, kidney disease, bleeding disorders, peptic ulcers.
Free of musculoskeletal injuries and limitations.
Abstain from dietary energy restriction.
Do not use medication such as anti-inflammatory drugs, antibiotics, antihypertensive drugs or anticoagulants.
4 more inclusion criteria and the exclusion criteria are on the listing.
What it tests, as registered
Placebo; NAC; NAC + Whey Protein
Registered summary
Previous evidence suggests that though N-acetylcysteine (NAC) supplementation following eccentric exercise-induced muscle damage disrupts the skeletal muscle's repair and remodelling process at 8 days of recovery, it attenuates substantially the decline of skeletal muscle performance during the first 48 hours of recovery. The enhanced performance capacity during the first phase of recovery in response to NAC supplementation might be attributed to the altered redox status in skeletal muscle as a consequence of the NAC-mediated elevation of reduced glutathione (GSH) levels. The full summary is on the listing.
Where, as registered
No US site; Greece (1).
RecruitingNCT06955975
The Effect of Pectin Supplementation on Geriatric With Frailty: A Randomised Placebo-Controlled Dietary Intervention Study
No phase
University of Nottingham
About 30 people
Started Feb 10, 2025
In plain words A study of whey protein in people 65 and older, run by University of Nottingham. It plans to enroll about 30 people at 1 site, none in the US.
Who it lists and where
Who the trial lists, as registered
Lists people 65 and older; healthy volunteers accepted. Conditions: Frailty at Older Adults; Pre-Frailty; Frailty; Diet; Dietary Fiber; Systemic Inflammatory Response.
Participant is willing and able to give informed consent for participation in the study.
Participant eligibility includes those aged >65 years who have a body mass index (BMI) between 18.5 and 39.9 kg/m2.
Participants who are considered as pre-frail or frail based on FRAIL (Simple Frailty Questionnaire).
The exclusion criteria are on the listing.
What it tests, as registered
Pectin; Whey protein
Registered summary
The study involves the intake of Low-methoxy (LM) pectin (polysaccharides extracted from citrus peels), which are commonly found in the UK diet (not pharmacological agents), to test their effects on systematic inflammation in the body and gut microbiome composition. The full summary is on the listing.
Where, as registered
No US site; United Kingdom (1).
RecruitingNCT07487623
Evaluation of the Hepatoprotective Effects of a Nutritional Supplement in Patients With Liver Disease Secondary to Chronic Hepatitis C Virus Infection (RESQUETI Study).
No phase
University of Guadalajara
About 26 people
Started Oct 11, 2025
In plain words A study of whey protein in people 18 to 69, run by University of Guadalajara. It plans to enroll about 26 people at 2 sites, none in the US.
Who it lists and where
Who the trial lists, as registered
Lists people 18 to 69. Conditions: Liver Disease Chronic; HEPATITIS C VIRUS CHRONIC INFECTION.
What it tests, as registered
resveratrol, quercetin, taurine, whey protein, and inulin; whey protein
Registered summary
The purpose of this clinical trial is to evaluate whether a nutritional supplement containing resveratrol, quercetin, taurine, inulin, and whey protein improves biochemical and molecular markers, as well as clinical outcomes, in patients with liver disease related to chronic hepatitis C infection. The study will compare the investigational supplement with an active control (whey protein alone) to determine whether the combination formulation provides additional benefits on liver-related biomarkers and clinical assessment. The full summary is on the listing.
Where, as registered
No US site; Mexico (2).
RecruitingNCT04871412
The Thoracic Peri-Operative Integrative Surgical Care Evaluation Trial - Stage III
Phase 3
Ottawa Hospital Research Institute
About 20 people
Started Apr 4, 2022
In plain words A Phase 3 study of whey protein in people 18 and older, run by Ottawa Hospital Research Institute. It plans to enroll about 20 people at 2 sites, none in the US.
Who it lists and where
Who the trial lists, as registered
Lists people 18 and older. Conditions: Lung Cancer; Gastric Cancer; Esophageal Cancer.
Adults eligible for complete resection of lung, gastric or esophageal cancer
The exclusion criteria are on the listing.
What it tests, as registered
Vitamin D3 Drops; Coriolus Versicolor; Trident SAP 66:33 Lemon; Probiotic Pro12; Provitalix Pure Whey Protein; Theracurmin 2X; Green Tea Extract; Nutrition Recommendations; Physical Activity Recommendations; Psychological Recommendations
Registered summary
Despite enormous advances in thoracic surgery and oncology, two critical issues concern patients undergoing curative-intent surgery for lung, gastric and esophageal cancer: first, a majority (\~60%) of patients experience minor and major adverse events occurring during and in the days following surgery; second, patients worry about the significant risk of cancer recurrence and mortality months to years after surgery. These issues, combined with side effects of chemotherapy and radiation, have detrimental effects on health-related quality of life (HRQoL). The full summary is on the listing.
Where, as registered
No US site; Canada (2).
RecruitingNCT07451496
PRecision gerOMedicinE: Tailored Healthy agEing With Lifestyle, sUpplements and drugS (PROMETHEUS)
No phase
National University of Singapore
About 20 people
Started Sep 29, 2025
In plain words A study of whey protein in people 50 to 80, run by National University of Singapore. It plans to enroll about 20 people at 1 site, none in the US.
Who it lists and where
Who the trial lists, as registered
Lists people 50 to 80; healthy volunteers accepted. Conditions: Ageing.
Age 50-80 years (both male and female)
Relatively healthy and in stable health condition
Not engaged in regular resistance or aerobic training in the past 12 months (i.e., untrained)
VO₂peak below the 75th percentile for age- and sex-specific norms
6 more inclusion criteria and the exclusion criteria are on the listing.
As the population ages, the growing prevalence of age-related diseases is creating substantial challenges for healthcare systems worldwide. Current therapeutic strategies often target individual diseases and decrease mortality without improving healthspan. The geroscience hypothesis suggests that targeting the ageing process itself could prevent, delay, or manage the severity of multiple age-related diseases concurrently, thereby improving overall healthspan and reducing healthcare burdens. The full summary is on the listing.
Where, as registered
No US site; Singapore (1).
RecruitingNCT06953232
Acute Impact of Whey Protein-enriched Milk Fat Globule Membrane Supplementation on Postprandial Markers of Heart and Brain Health
No phase
Loughborough University
About 16 people
Started Sep 30, 2025
In plain words A study of whey protein in female participants 50 to 75, run by Loughborough University. It plans to enroll about 16 people at 1 site, none in the US.
In a single-blind, randomised, placebo-controlled crossover manner, this study aims to assess the impact of a high-fat mixed meal containing a whey protein (WP)-enriched milk fat globule membrane (MFGM) powdered ingredient on markers of heart and brain health in the fed state among middle-to-older-aged, postmenopausal women living with overweight and at moderate risk for cardiovascular disease. Participants will attend two \~8 hour study visits, where they will consume a high-fat meal containing a WP-enriched MFGM powdered ingredient or a placebo WP-based powdered ingredient. The full summary is on the listing.
Where, as registered
No US site; United Kingdom (1).
RecruitingNCT07148908
Animal and Microbial-based Dietary Protein Efficiency in Adults
No phase
Daniel Moore
About 13 people
Started Jul 1, 2025
In plain words A study of whey protein in people 18 to 45, run by Daniel Moore. It plans to enroll about 13 people at 1 site, none in the US.
Who it lists and where
Who the trial lists, as registered
Lists people 18 to 45; healthy volunteers accepted. Conditions: Protein Metabolism.
Healthy, male and female, recreationally-active participants.
Healthy will be defined as screened by the PAR-Q+ (Appendix B) and The Physical Activity Readiness Questionnaire (Appendix C).
Participants will be aged 18-45 years old.
Participants are willing to abide by the compliance rules of this study.
2 more inclusion criteria and the exclusion criteria are on the listing.
What it tests, as registered
Yeast Protein Supplement; Whey Protein Isolate Supplement; Collagen Hydrolysate Supplement
Registered summary
Given the relatively high carbon footprint and sustainability of animal-based proteins, there is a growing interest in determining the nutritional quality non-animal-based protein sources. The overall objective of this investigation is to examine the impact of different animal and microbial-based protein sources to support whole body protein synthesis in adults. To do this, investigators will employ a 'breath test' method developed in our laboratory as well as urine sampling. The full summary is on the listing.
Where, as registered
No US site; Canada (1).
RecruitingNCT07082309
The Effect of Ketone Monoesters on Skeletal Muscle Protein Synthesis and Whole-body Protein Metabolism.
No phase
University of Exeter
About 12 people
Started Jun 4, 2025
In plain words A study of whey protein in people 18 to 40, run by University of Exeter. It plans to enroll about 12 people at 1 site, none in the US.
Who it lists and where
Who the trial lists, as registered
Lists people 18 to 40; healthy volunteers accepted. Conditions: Healthy Participants.
BMI 18-30
The exclusion criteria are on the listing.
What it tests, as registered
Ketone Monoester (KE) and whey protein beverage; Control
Registered summary
The ketone β-hydroxybutyrate (BHB) is endogenously produced during periods of low glucose availability, serving as an alternative metabolic fuel. Beyond its role as an energy substrate, BHB acts as a pleiotropic signalling molecule, modulating various physiological processes across multiple tissues. BHB can also be ingested orally as a ketone monoester, transiently elevating plasma concentrations of BHB to a level similar to those seen following several days of fasting, thereby obviating the need for dietary manipulation. The full summary is on the listing.
Where, as registered
No US site; United Kingdom (1).
Not yet recruitingNCT06967428
Effect of Metabolic Modulation on a Post-acute COVID-19 Vaccination Syndrome (PACVS) Cohort
Phase 2
Independent Medical Alliance
About 100 people
Starts Sep 1, 2025 (estimated)
In plain words A Phase 2 study of whey protein in people 16 and older, run by Independent Medical Alliance. It plans to enroll about 100 people at 1 US site.
Who it lists and where
Who the trial lists, as registered
Lists people 16 and older. Conditions: Vaccine Adverse Reaction; Post Acute Covid-19 Vaccination Syndrome.
Persistent fatigue lasting more than 6 months
Received at least one dose of a Covid-19 vaccine, after which they experienced fatigue symptoms (symptom onset within two weeks of vaccination)
Laboratory result showing persistent spike protein in blood OR presence of spike protein antibodies with SARS-CoV-2 nucleocapsid antibodies negative.
The exclusion criteria are on the listing.
What it tests, as registered
Combined metabolic modulator; Rice Protein Powder with Vitamin C
Registered summary
The goal of this clinical trial is to evaluate whether metabolic modulation with a combined nutraceutical product can improve symptoms and metabolic health in adults diagnosed with post-acute Covid-19 vaccination syndrome (PACVS), a condition characterized by persistent fatigue and exercise intolerance attributed to Covid-19 vaccination and confirmed by laboratory testing. The full summary is on the listing.
Where, as registered
1 US site in 1 state.
Not yet recruitingNCT07531563
Protein Supplementation for Radiation- Induced Oral Mucositis in Head and Neck Cancer Patients Receiving Radiotherapy
No phase
Cancer Institute and Hospital, Chinese Academy of Medical Sciences
About 504 people
Starts Jul 1, 2026 (estimated)
In plain words A study of whey protein in people 18 to 75, run by Cancer Institute and Hospital, Chinese Academy of Medical Sciences. It plans to enroll about 504 people and lists no sites yet.
Who it lists and where
Who the trial lists, as registered
Lists people 18 to 75. Conditions: Head & Neck Cancer.
Age 18-75 years
Histologically confirmed squamous cell carcinoma of the oral cavity, oropharynx, hypopharynx, or larynx
No distant metastases (M0 stage)
Planned to receive curative or postoperative radiotherapy (with or without concurrent therapy) with a mean oral cavity dose ≥20 Gy
3 more inclusion criteria and the exclusion criteria are on the listing.
What it tests, as registered
Hydrolyzed Whey Protein Oral Supplement; Control
Registered summary
This clinical trial aims to evaluate whether oral supplementation with a hydrolyzed whey protein formula ("TeYiShu") can reduce the incidence of severe radiation-induced oral mucositis and improve prealbumin levels in patients undergoing radiotherapy for head and neck squamous cell carcinoma (HNSCC). The study will compare the protein supplement to an isocaloric placebo without protein, maintaining equal caloric intake across groups. Participants will receive either the protein supplement or placebo daily throughout the course of radiotherapy. The full summary is on the listing.
Where, as registered
No sites listed yet.
Not yet recruitingNCT07049731
Improvement of Skeletal and Muscle Health in Patients With Sarcopenia by Protein Powder With Resistance Exercise
No phase
Weiwei Ma
About 224 people
Starts Aug 2025 (estimated)
In plain words A study of whey protein in people 35 to 75, run by Weiwei Ma. It plans to enroll about 224 people at 1 site, none in the US.
Who it lists and where
Who the trial lists, as registered
Lists people 35 to 75. Conditions: Sarcopenia.
Meet the diagnostic criteria for sarcopenia AWGS 2019
Grip strength less than 28.0 kg for males and less than 18.0 kg for females
6-meter stride speed less than 1.0 m/s or 5-repetition sit-up test time ≥ 12 seconds or SPPB ≤ 9 points.
Bioelectrical Impedance Analysis (BIA) less than 7.0 kg/m² for males and 5.7 kg/m² for females or Dual-energy X-ray absorptiometry (DXA) less than 7.0 kg/m² for males and 5.4 kg/m² for females;
3 more inclusion criteria and the exclusion criteria are on the listing.
What it tests, as registered
Protein powder intervention; Resistance exercise intervention; Placebo control
Registered summary
Sarcopenia is an age-related progressive skeletal muscle disease, the prevalence of which is increasing year by year with the aging of China's population, seriously affecting the health and quality of life of the elderly. Relevant studies have shown that protein intake in combination with resistance exercise can significantly improve muscle mass and function, and the effect is superior to that of a single intervention. The full summary is on the listing.
Where, as registered
No US site; China (1).
Not yet recruitingNCT07295301
Protein Intake Dosage on the Prognosis of Neurocritical Patients
No phase
Wenshan City People's Hospital
About 216 people
Starts Dec 2025 (estimated)
In plain words A study of whey protein in people 18 to 80, run by Wenshan City People's Hospital. It plans to enroll about 216 people and lists no sites yet.
Who it lists and where
Who the trial lists, as registered
Lists people 18 to 80. Conditions: Neurocritical Conditions; Traumatic Brain Injury; Ischemic Stroke.
What it tests, as registered
Low-Dose Enteral Protein Supplementation (Enteral Nutrition Formulas + Whey Protein Powder); Moderate-Dose Enteral Protein Supplementation (Enteral Nutrition Formulas + Whey Protein Powder); High-Dose Enteral Protein Supplementation (Enteral Nutrition Formulas + Whey Protein Powder)
Registered summary
This study investigates the effect of different early protein supplementation levels (1.0-2.0g/kg/d, divided into three groups) on the prognosis of neurocritical patients, focusing on the 28-day Glasgow Coma Scale (GCS) score improvement rate. Participants will be randomly assigned to receive varying protein doses, and their short-term (28-day mortality, ICU stay, complications) and long-term (90-day mortality, readmission rate) clinical outcomes will also be compared.
Where, as registered
No sites listed yet.
Not yet recruitingNCT07817823
Yeast Protein Supplementation and Muscle Preservation During GLP-1RA-Induced Weight Loss
No phase
Huazhong University of Science and Technology
About 200 people
Starts Sep 20, 2026 (estimated)
In plain words A study of whey protein in people 25 to 50, run by Huazhong University of Science and Technology. It plans to enroll about 200 people at 1 site, none in the US.
Who it lists and where
Who the trial lists, as registered
Lists people 25 to 50. Conditions: Overweight and Obesity in Adults Receiving GLP-1RA Treatment.
Adults aged 25-50 years with overweight or obesity, defined as BMI ≥24.0 kg/m², who meet the clinical indication for GLP-1RA-related weight-loss treatment.
The exclusion criteria are on the listing.
What it tests, as registered
Yeast Protein; Whey Protein; Yeast Protein/Whey Protein Blend (1:1)
Registered summary
The goal of this clinical trial is to evaluate whether yeast protein supplementation can help preserve lean body mass and muscle function in adults with overweight or obesity receiving GLP-1 receptor agonist-related treatment for weight loss. The main questions it aims to answer are: 1. Does yeast protein supplementation reduce the loss of lean body mass during GLP-1RA-related weight loss? 2. Does yeast protein supplementation improve or preserve muscle function? 3. The full summary is on the listing.
Where, as registered
No US site; China (1).
Not yet recruitingNCT06950684
Impact of Protein Supplementation and Resistance Training on Body Composition, Functional Parameters, Metabolic Adaptation, and Nitrogen Balance in Adults Aged 45 Years and Older With Overweight or Obesity Receiving Incretin-based Medications
No phase
Assuta Medical Center
About 180 people
Starts Jul 1, 2025 (estimated)
In plain words A study of whey protein in people 45 and older, run by Assuta Medical Center. It plans to enroll about 180 people and lists no sites yet.
Who it lists and where
Who the trial lists, as registered
Lists people 45 and older. Conditions: Obesity; Overweight (BMI > 25); Weight Loss.
Adults aged ≥45 years.
Overweight or obese (BMI ≥30, or BMI ≥27 with at least one obesity-related comorbidity).
Eligible to receive incretin-based weight loss medications (e.g. Wegovy or Mounjaro).
Able to read and speak Hebrew fluently.
The exclusion criteria are on the listing.
What it tests, as registered
Whey Protein Supplement; Resistance Training Program
Registered summary
This study aim to evaluate the effects of protein supplements and resistance training on body composition, functional parameters, metabolic adaptation, and nitrogen balance in adults (aged ≥45 years) with overweight/obesity receiving weekly Incretin-Based obesity management medication treatment for 6 months. A parallel design, open-label, multicenter randomized controlled trial will be conducted among 240 patients (aged ≥45 years) initiating Incretin-Based obesity management medication. The full summary is on the listing.
Where, as registered
No sites listed yet.
Not yet recruitingNCT07449507
Partially Hydrolyzed Whey Protein Formula for Infants With Mild Allergy
No phase
Ruijin Hospital
About 160 people
Starts Jan 1, 2027 (estimated)
In plain words A study of whey protein in people 12 weeks to 20 weeks, run by Ruijin Hospital. It plans to enroll about 160 people and lists no sites yet.
Who it lists and where
Who the trial lists, as registered
Lists people 12 weeks to 20 weeks. Conditions: Mild Allergic Symptoms in Infants; Infant Feeding Intolerance.
Infants aged ≥12 weeks and <20 weeks at the time of screening.
Gestational age ≥37 weeks.
Birth weight ≥2500g.
Presence of mild allergic symptoms (e.g., skin, gastrointestinal, or respiratory symptoms).
2 more inclusion criteria and the exclusion criteria are on the listing.
What it tests, as registered
Partially Hydrolyzed Whey Protein Formula; Intact Cow's Milk Protein Formula
Registered summary
This study is a prospective, multicenter, randomized controlled trial designed to evaluate the clinical efficacy, tolerance, and safety of a partially hydrolyzed whey protein formula in infants with mild allergic symptoms. Partially hydrolyzed formulas contain low-molecular weight peptides and have been shown to improve protein tolerance and digestibility and to reduce allergenicity compared with intact cow's milk protein formulas. However, evidence regarding their therapeutic effects in infants who have already developed allergic symptoms remains limited. The full summary is on the listing.
Where, as registered
No sites listed yet.
Not yet recruitingNCT07801469
Nutritional Optimization in Anemic Patients Scheduled for Elective Open-Heart Surgery
Phase 3
National Institute of Cardiovascular Diseases, Pakistan
About 140 people
Starts Sep 10, 2026 (estimated)
In plain words A Phase 3 study of whey protein in people 18 to 70, run by National Institute of Cardiovascular Diseases, Pakistan. It plans to enroll about 140 people and lists no sites yet.
Who it lists and where
Who the trial lists, as registered
Lists people 18 to 70. Conditions: Anemia, Iron Deficiency.
Adult patients (≥18 years) scheduled for elective open heart surgery (CABG), with a minimum preoperative waiting period of 8-12 weeks and presenting with preoperative hemoglobin levels of 10-11 g/dL in females and 11-12 g/dL in males, were…
Moderate to good LV (EF 40 and above)
The exclusion criteria are on the listing.
What it tests, as registered
Immune Modulating Formula, Whey Protein, Multivitamins and Iron Supplements
Registered summary
1. To test the effect and feasibility of culturally relevant SNP program in Anaemic patients scheduled for elective open-heart surgery versus those getting usual preoperative care in a public sector hospital. 2. To evaluate the incidence of transfusion during intra-operative and postoperative periods among cardiac patients undergoing elective open-heart surgery who receive iron correction therapy as part of the Solo Nutrition Prehabilitation (SNP) program
Where, as registered
No sites listed yet.
Not yet recruitingNCT07722806
A Nutrition and Exercise Program With Olanzapine Compared to Olanzapine Alone: A Trial in Patients With Advanced Tumors
Phase 2
Kantonsspital Winterthur KSW
About 130 people
Starts Aug 2026 (estimated)
In plain words A Phase 2 study of whey protein in people 18 to 100, run by Kantonsspital Winterthur KSW. It plans to enroll about 130 people at 1 site, none in the US.
Who it lists and where
Who the trial lists, as registered
Lists people 18 to 100. Conditions: Cancer, Advanced Solid Tumors; Malnutrition.
Age ≥18 years
Metastatic or locally advanced solid tumors, excluding lymphoma, not eligible for curative treatment
VAS score ≤70 for appetite, as defined for anorexia in oncology patients (olanzapine is prescribed according to clinical guidelines as part of standard care)
WHO-PS of ≤3
3 more inclusion criteria and the exclusion criteria are on the listing.
What it tests, as registered
Standardized nutritional program; standardized exercize program; Whey protein supplement with added leucine and β-hydroxy-β-methylbutyrate (HMB)
Registered summary
Cancer patients have a higher risk of malnutrition because of their illness and treatments. This can lead to weight loss, weak muscles, less effective cancer therapy, or stronger side effects. This research project looks at whether adding a combined nutrition and exercise program to the standard treatment for appetite loss (olanzapine) can improve the quality of life for patients with cancer, compared to taking olanzapine alone. In this study, patients are randomly split into two groups. The program group gets advice from nutrition experts and physiotherapists. The full summary is on the listing.
Where, as registered
No US site; Switzerland (1).
Not yet recruitingNCT07561619
Yeast Protein for Muscle Mass
Phase 2 and 3
University of Alberta
About 72 people
Starts Nov 2026 (estimated)
In plain words A Phase 2 and 3 study of whey protein in people 18 to 35, run by University of Alberta. It plans to enroll about 72 people at 1 site, none in the US.
Who it lists and where
Who the trial lists, as registered
Lists people 18 to 35; healthy volunteers accepted. Conditions: Healthy Adult Participants.
Participants must have the ability to read, understand, and sign an informed consent form and must be willing to comply with study treatment and follow-up.
Prior resistance training experience (defined as performing resistance exercises >1/week for the past 3 months or longer) to enable them to reach a large training stimulus relatively quickly and to avoid the longer phase of neuromuscular…
≥18 years and <35 years of age
The exclusion criteria are on the listing.
What it tests, as registered
Yeast Protein; Resistance Training Exercises; Whey Protein
Registered summary
Protein supplementation is said to be one of the cost-efficient and practical strategies to meet protein needs for growth and exercise, and can help maximize muscle gain from resistance exercise. It facilitates faster recovery from stress-induced tissue damage and enhances performance output. Protein sources derived from animal products are generally recognized as the highest quality protein. However, altering the protein composition of a protein source can improve the protein quality. The full summary is on the listing.
Where, as registered
No US site; Canada (1).
Not yet recruitingNCT07759271
Effects of Whey Protein and Resistance Training on Muscle Mass in Patients With Intestinal Failure
No phase
Wang Xinying
About 72 people
Starts Aug 28, 2026 (estimated)
In plain words A study of whey protein in people 18 to 65, run by Wang Xinying. It plans to enroll about 72 people and lists no sites yet.
Who it lists and where
Who the trial lists, as registered
Lists people 18 to 65. Conditions: Intestinal Failure; Low Muscle Mass.
Patients with chronic intestinal failure and low muscle mass.
Willing to participate in the study and provide written informed consent.
Able to complete the assigned 6-week intervention and the assessments at baseline, week 6, and week 8.
The exclusion criteria are on the listing.
What it tests, as registered
Whey Protein Supplementation Group; Resistance Training Group
Registered summary
This single-center, prospective, four-arm randomized controlled trial will enroll 72 adults with chronic intestinal failure and low muscle mass. All participants will receive standardized basic nutritional support and will be randomly assigned to one of four groups: usual care, whey protein supplementation, resistance training, or whey protein supplementation combined with resistance training. Participants assigned to whey protein supplementation will receive 20 g of whey protein daily for 6 weeks. The full summary is on the listing.