Vitamin A (retinyl palmitate vs beta-carotene) trials recruiting now
5 registrations that name vitamin A as a study arm and are recruiting or about to, as ClinicalTrials.gov listed them on Oct 20, 2026. Read each listing for its full criteria and current status.
Kymata never assesses eligibility. Each listing names its own criteria; only its study team can say whether someone can join. Trial doses are given under the trial's monitoring and are not a schedule for anyone outside it.
Filter 5 registrations
Status
Phase
5US sites across 5 states
1
2 to 4
5 to 19
20 or more
All 5 registrations
RecruitingNCT06450925
Vitamin A Supplementation in Allogeneic Stem Cell Transplantation.
Phase 2
Children's Hospital Medical Center, Cincinnati
About 190 people
Started Mar 25, 2025
In plain words A Phase 2 study of vitamin A in people 18 and older, run by Children's Hospital Medical Center, Cincinnati. It plans to enroll about 190 people at 3 US sites.
Who it lists and where
Who the trial lists, as registered
Lists people 18 and older. Conditions: Graft Vs Host Disease; Vitamin A Deficiency; Vitamin D Deficiency.
Be 18 years of age or older
Be scheduled for allogeneic stem cell transplant.
Have a vitamin A level < upper limit of normal for age.
Be able to tolerate enteral vitamin dose administration.
2 more inclusion criteria and the exclusion criteria are on the listing.
What it tests, as registered
Vitamin A; Placebo
Registered summary
The investigators hypothesize that single oral high dose supplementation with vitamin A will reduce the incidence of moderate-severe chronic graft-versus-host disease (GVHD) compared with placebo.
Where, as registered
3 US sites in 3 states.
RecruitingNCT05702398
Pilot Trial of Supplemental Vitamin A and Nicotinamide
Early phase 1
Rhode Island Hospital
About 30 people
Started Apr 1, 2023
In plain words An early phase 1 study of vitamin A in people 18 and older, run by Rhode Island Hospital. It plans to enroll about 30 people at 1 US site.
Who it lists and where
Who the trial lists, as registered
Lists people 18 and older. Conditions: Skin Cancer; Kidney Transplant Recipients.
18 years old or greater;
Either History of 2 or more histologically confirmed invasive cutaneous SCCs in the past 2 years or
At least one previously billed Healthcare Common Procedure Coding System code 17004 (destruction of 15 or more benign or premalignant lesions of the integumentary system);
Understands, reads, and writes English proficiently.
The exclusion criteria are on the listing.
What it tests, as registered
Vitamin A; Nicotinamide; Other: Placebo
Registered summary
The goal of this clinical trial is to assess the feasibility and safety of oral nicotinamide (NAM; a derivative of vitamin B3 \[niacin\]) and vitamin A in a high-risk population of kidney transplant recipients with a history of skin cancer to generate preliminary data for future cancer prevention clinical trials.
Where, as registered
1 US site in 1 state.
RecruitingNCT06508099
Vitamin A and D Supplementation in Allogeneic HCT
Phase 2
St. Petersburg State Pavlov Medical University
About 220 people
Started May 15, 2024
In plain words A Phase 2 study of vitamin A in people 18 and older, run by St. Petersburg State Pavlov Medical University. It plans to enroll about 220 people at 1 site, none in the US.
Standard disease risk: less than 5% clonal blasts in the bone marrow and the absence of blast forms in the peripheral blood at the time of inclusion in the study or at least partial response for lymphoproliferative neoplasms.
Related compatible donor 10/10 HLA-matched or unrelated compatible donor 9-10/10 HLA-matched
Age ≥18 years
1 more inclusion criterion and the exclusion criteria are on the listing.
What it tests, as registered
Vitamin A; Vitamin D3
Registered summary
The therapy under investigation is the addition of 300 000 IU of vitamin A and 100 000 IU of vitamin D before conditioning. The study will include patients with malignant diseases in hematologic response with indications for allogeneic transplantation with matched related or matched unrelated donor.
Where, as registered
No US site; Russia (1).
RecruitingNCT07335991
Effect of Vitamin A Supplementation on Idiopathic Scoliosis
No phase
Second Affiliated Hospital of Wenzhou Medical University
About 140 people
Started May 13, 2025
In plain words A study of vitamin A in people 6 to 15, run by Second Affiliated Hospital of Wenzhou Medical University. It plans to enroll about 140 people at 1 site, none in the US.
Who it lists and where
Who the trial lists, as registered
Lists people 6 to 15. Conditions: Vitamin A Deficiency; Idiopathic Scoliosis.
Age between 6 and 15 years.
Biochemically confirmed vitamin A deficiency (serum retinol < 0.20 mg/L) or insufficiency (serum retinol 0.20-0.29 mg/L).
Has undergone radiographic evaluation (standing full-spine X-ray) for idiopathic scoliosis at the initial clinic visit.
Skeletally immature (Risser sign 0-3) with a major Cobb angle < 40 degrees at baseline.
1 more inclusion criterion and the exclusion criteria are on the listing.
What it tests, as registered
Vitamin A; Nutritional Education
Registered summary
This study aims to investigate whether vitamin A supplementation can influence spinal curve magnitude in idiopathic scoliosis children and potentially prevent its de novo development.
Where, as registered
No US site; China (1).
Not yet recruitingNCT07736768
Vitamin A Supplementation and Breast Milk Vitamin A Levels in Mothers of Preterm Infants
No phase
University of Mississippi Medical Center
About 20 people
Starts Aug 1, 2026 (estimated)
In plain words A study of vitamin A in people 18 to 45, run by University of Mississippi Medical Center. It plans to enroll about 20 people at 1 US site.
Who it lists and where
Who the trial lists, as registered
Lists people 18 to 45. Conditions: Premature; Preterm Infant Health; Vitamin A Deficiency; Human Milk; Breastfeeding.
Mothers aged 18 to 45 years Delivered an infant born at less than 29 weeks' gestation Intending to provide breast milk for at least 4 months postpartum Willing and able to swallow oral tablets Willing to comply with study procedures,…
The exclusion criteria are on the listing.
What it tests, as registered
Oral multivitamin containing vitamin A
Registered summary
Preterm infants are at increased risk of vitamin A deficiency because they are born with low vitamin A stores and depend largely on breast milk to meet their nutritional needs. This study will evaluate whether daily maternal vitamin A supplementation increases vitamin A concentrations in the breast milk of mothers who deliver infants before 29 weeks of gestation. Participants will receive a commercially available oral multivitamin supplement containing 1,300 mcg retinol activity equivalents (RAE) of vitamin A daily for four months after delivery. The full summary is on the listing.