Royal jelly trials recruiting now

5 registrations that name royal jelly as a study arm and are recruiting or about to, as ClinicalTrials.gov listed them on Oct 20, 2026. Read each listing for its full criteria and current status.

Kymata never assesses eligibility. Each listing names its own criteria; only its study team can say whether someone can join. Trial doses are given under the trial's monitoring and are not a schedule for anyone outside it.

Filter 5 registrations

Status

All 5 registrations

RecruitingNCT06288204

Green Propolis Extract and Royal Jelly in Hypertensive Patients and/or With Chronic Kidney Disease

  • No phase
  • Universidade Federal Fluminense
  • About 153 people
  • Started Oct 1, 2024

In plain words A study of royal jelly in people 18 to 75, run by Universidade Federal Fluminense. It plans to enroll about 153 people at 2 sites, none in the US.

Who it lists and where

Who the trial lists, as registered

Lists people 18 to 75. Conditions: Chronic Kidney Diseases; Hypertension; Cardiovascular Diseases.

  • patients in stages 3 and 5 of CKD (GFR from 15 to 59 mL/min),
  • patients receiving ambulatorial nutrition treatment at least 6 months
  • patients on regular Hemodialysis treatment for at least 6 months
  • patients using one to three antihypertensive drugs

The exclusion criteria are on the listing.

What it tests, as registered

Propolis associated with Royal Jelly; Royal Jelly; Placebo

Registered summary

This work aims to evaluate the effects of the association of green propolis extract with royal jelly on inflammation and oxidative stress in participants with chronic kidney diseases (CKD) and Systemic arterial hypertension (SAH), in a longitudinal, randomized, double-blind, placebo-controlled clinical trial that will be carried out for 2 months.

Where, as registered

No US site; Brazil (2).

RecruitingNCT07337265

Royal Jelly Supplementation in Unexplained Male Infertility

  • No phase
  • Medipol University
  • About 80 people
  • Started Feb 1, 2026

In plain words A study of royal jelly in male participants 18 to 45, run by Medipol University. It plans to enroll about 80 people at 1 site, none in the US.

Who it lists and where

Who the trial lists, as registered

Lists male participants 18 to 45. Conditions: Unexplained Infertility; Male Infertility; Sperm DNA Fragmentation.

  • Men aged 18-45 years. History of infertility for at least 1 year despite unprotected intercourse.

The exclusion criteria are on the listing.

What it tests, as registered

Lyophilized Royal Jelly; Placebo

Registered summary

This randomized, double-blind, placebo-controlled clinical trial investigates the effects of oral Royal Jelly supplementation on sperm DNA fragmentation and pregnancy rates in couples with unexplained infertility. While routine semen analysis appears normal (normozoospermia) in these patients, underlying Sperm DNA Fragmentation (SDF) and oxidative stress are believed to contribute to reproductive failure. Participants will be randomized to receive either 750 mg of lyophilized Royal Jelly or a placebo daily for a period of 3 months (90 days). The full summary is on the listing.

Where, as registered

No US site; Turkey (Türkiye) (1).

RecruitingNCT07596966

EFFECTS OF PROPOLIS AND ROYAL JELLY SUPPLEMENTATION ON INFLAMMATORY AND OXIDATIVE STRESS MARKERS IN PATIENTS WITH SYSTEMIC ARTERIAL HYPERTENSION

  • No phase
  • Universidade Federal Fluminense
  • About 48 people
  • Started Oct 15, 2025

In plain words A study of royal jelly in people 18 to 75, run by Universidade Federal Fluminense. It plans to enroll about 48 people at 1 site, none in the US.

Who it lists and where

Who the trial lists, as registered

Lists people 18 to 75. Conditions: Systemic Arterial Hypertension; Inflammation.

  • Diagnosis of stage 1 and 2 hypertension
  • Regular treatment for more than 6 months
  • There have been no changes in medication doses over the last three months.

The exclusion criteria are on the listing.

What it tests, as registered

Placebo; Royal Jelly + Propolis Group

Registered summary

The study aims to evaluate the effect of the royal jelly and propolis on inflammation and oxidative stress in participants with systemic arterial hypertension. A longitudinal double-blind randomized clinical trial will be carried out, involving hypertensive participants for two months.

Where, as registered

No US site; Brazil (1).

RecruitingNCT06917131

Royal Jelly as a Strategy to Modulate Inflammation and Oxidative Stress in Patients With Systemic Arterial Hypertension

  • No phase
  • Universidade Federal Fluminense
  • About 34 people
  • Started Sep 18, 2024

In plain words A study of royal jelly in people 18 to 75, run by Universidade Federal Fluminense. It plans to enroll about 34 people at 1 site, none in the US.

Who it lists and where

Who the trial lists, as registered

Lists people 18 to 75. Conditions: Hypertension; Cardiovascular Diseases (CVD); Inflammation.

  • Diagnosis of stage 1 hypertension
  • Regular treatment for more than 6 months
  • No changes in medication doses during the last 3 months

The exclusion criteria are on the listing.

What it tests, as registered

Royal Jelly; Placebo

Registered summary

The study aims to evaluate the effect of the royal jelly on inflammation and oxidative stress in participants with systemic arterial hypertension. A longitudinal double-blind randomized clinical trial will be carried out, involving hypertensive participants for two months.

Where, as registered

No US site; Brazil (1).

Not yet recruitingNCT07596992

Effects of Royal Jelly and Propolis on Metabolomic Signatures, Inflammation, and Cardiovascular Risk in Patients With Coronary Artery Disease.

  • No phase
  • Universidade Federal Fluminense
  • About 50 people
  • Starts May 18, 2026 (estimated)

In plain words A study of royal jelly in people 18 and older, run by Universidade Federal Fluminense. It plans to enroll about 50 people at 1 site, none in the US.

Who it lists and where

Who the trial lists, as registered

Lists people 18 and older. Conditions: Coronary Artery Disease (CAD); Oxidative Stress; Inflammation.

  • Both sexes
  • Over 18 years of age;
  • Diagnosed with Coronary Artery Disease: confirmed by coronary angiography, coronary computed tomography angiography, or functional testing with ischemic load);
  • Participants who are asymptomatic or have angina limited to functional class III will be considered;

2 more inclusion criteria and the exclusion criteria are on the listing.

What it tests, as registered

Propolis + Royal Jelly; Placebo

Registered summary

The aim of this project is to evaluate the effect of bioactive compound sources, propolis and royal jelly, on metabolomics, inflammation, and cardiovascular risk markers in participants with coronary artery disease. A longitudinal double-blind randomized clinical trial will be carried out, involving CAD participants for two months.

Where, as registered

No US site; Brazil (1).

ClinicalTrials.gov lists 20 open registrations for this search, including ones where royal jelly is not a study arm or that are past the 5 we keep. Search them on ClinicalTrials.gov (opens in new tab).

Educational only. Not medical advice. Some links earn us a commission: kymatahealth.com/affiliate-disclosure.