5 registrations that name psyllium as a study arm and are recruiting or about to, as ClinicalTrials.gov listed them on Oct 20, 2026. Read each listing for its full criteria and current status.
Kymata never assesses eligibility. Each listing names its own criteria; only its study team can say whether someone can join. Trial doses are given under the trial's monitoring and are not a schedule for anyone outside it.
Filter 5 registrations
Status
Phase
1US sites across 1 state
1
2 to 4
5 to 19
20 or more
All 5 registrations
RecruitingNCT06639984
Psyllium in Pediatric IBS
Phase 2
Dr Bruno Chumpitazi, M.D.
About 110 people
Started Feb 20, 2025
In plain words A Phase 2 study of psyllium in people 12 to 17, run by Dr Bruno Chumpitazi, M.D.. It plans to enroll about 110 people at 1 US site.
Who it lists and where
Who the trial lists, as registered
Lists people 12 to 17. Conditions: Irritable Bowel Syndrome.
Children between the ages of 12-17 years meeting pediatric Rome IV criteria for IBS
The exclusion criteria are on the listing.
What it tests, as registered
Psyllium (0.7 g/year of age per day); Psyllium (0.5 g/year of age per day); Placebo; fructans
Registered summary
The goal of this clinical trial is to learn if a fiber (psyllium) can change the way bacteria use fructans (a type of sugar) and whether psyllium can help decrease childhood irritable bowel syndrome (IBS) symptoms when eating fructans. The main questions it aims to answer are: Aim 1: The effect of psyllium at two doses given with a fructan meal on microbial fructan fermentation (intracolonic pH; H2 gas production; gut microbiome composition; fecal short-chain fatty acids, lactate, glycomics). Aim 2: Determine the impact of psyllium given with a fructan meal on fructan-induced GI symptoms. The full summary is on the listing.
Where, as registered
1 US site in 1 state.
RecruitingNCT06492200
Impact of a High-fiber Diet on the Microbiome and Disease Activity in Patients With Rheumatoid Arthritis
No phase
Wuerzburg University Hospital
About 52 people
Started Jun 1, 2024
In plain words A study of psyllium in people 18 to 99, run by Wuerzburg University Hospital. It plans to enroll about 52 people at 1 site, none in the US.
Who it lists and where
Who the trial lists, as registered
Lists people 18 to 99. Conditions: Arthritis, Rheumatoid.
Patients over 18 years old
Diagnosis of Rheumatoid Arthritis according to the ACR criteria of 2010
The patient can understand the scope of the study and consents in writing to participate.
The exclusion criteria are on the listing.
What it tests, as registered
Psyllium husks
Registered summary
The goal of this clinical trial is to learn if increasing dietary fiber can improve the gut microbiome and reduce disease activity in adults with rheumatoid arthritis (RA). The main questions it aims to answer are: * Can a higher fiber diet improve gut bacteria and produce beneficial short-chain fatty acids (SCFAs)? * Does a higher fiber diet reduce RA symptoms and help with weight loss? Researchers will compare two groups: one group will receive dietary counseling and take 10 grams of psyllium husk daily, while the other group will continue their usual diet. The full summary is on the listing.
Where, as registered
No US site; Germany (1).
RecruitingNCT07202481
Chronic Ingestion of Fructooligosaccharide and Psyllium on Intestinal Transit in Women With Functional Constipation: A Randomized Crossover Trial
No phase
Federal University of Minas Gerais
About 25 people
Started Mar 14, 2026
In plain words A study of psyllium in female participants 18 to 59, run by Federal University of Minas Gerais. It plans to enroll about 25 people at 1 site, none in the US.
Who it lists and where
Who the trial lists, as registered
Lists female participants 18 to 59. Conditions: Constipation - Functional.
Female participants aged 18-59 years.
Willingness to sign the Informed Consent Form .
No restrictions on the consumption of egg or gluten.
No history or diagnosis of gastrointestinal diseases other than functional constipation.
7 more inclusion criteria and the exclusion criteria are on the listing.
What it tests, as registered
Psyllium powder; Fructooligosaccharide
Registered summary
The goal of this clinical trial is to evaluate the effect of dietary fibers in the treatment of functional constipation in women. It will also assess the potential side effects associated with fiber consumption. The main questions it aims to answer are: * In women with constipation who do not consume adequate dietary fiber, does supplementation help improve bowel function? * Among the fibers studied, is there any hierarchy of effect in the treatment of constipation (i.e., is one more effective than the other)? The researchers will compare the effects of the two dietary fibers against each… The full summary is on the listing.
Where, as registered
No US site; Brazil (1).
Not yet recruitingNCT06785831
NutriPlant - Opportunities for Increasing Consumption of Local Fruits and Vegetables
No phase
Institute of Nutrition, Slovenia (Nutris)
About 120 people
Starts Jan 20, 2025 (estimated)
In plain words A study of psyllium in people 18 to 70, run by Institute of Nutrition, Slovenia (Nutris). It plans to enroll about 120 people at 1 site, none in the US.
Who it lists and where
Who the trial lists, as registered
Lists people 18 to 70. Conditions: Functional Constipation; Irritable Bowel Syndrome.
Inclusion criteria:
Signed informed consent of the participant to participate in the study
Age between 18 and 70 years
Functional constipation or irritable bowel syndrome
10 more inclusion criteria and the exclusion criteria are on the listing.
What it tests, as registered
Psyllium; Sauerkraut; Fresh apples; Dried apples
Registered summary
The effects of different foods to normal bowel function in adult population will be investigated. A randomised controlled intervention trial will be conducted on about 120 (30 per group) adult (18-70 years) subjects with functional constipation and irritable bowel syndrome with constipation according to the IV. Rome criteria. At least one week before inclusion in the study, patients will stop taking laxatives and other anti-constipation medications. The full summary is on the listing.
Where, as registered
No US site; Slovenia (1).
Not yet recruitingNCT07880327
Psyllium Husk in Pediatric IBS
No phase
Eman ElHaddad
About 70 people
Starts Oct 10, 2026 (estimated)
In plain words A study of psyllium in people 6 to 18, run by Eman ElHaddad. It plans to enroll about 70 people and lists no sites yet.
Who it lists and where
Who the trial lists, as registered
Lists people 6 to 18. Conditions: Prebiotic; IBS (Irritable Bowel Syndrome); Psyllium; Quality of Life (QOL).
Children aged 6-18 years.
Meet the diagnostic criteria for irritable bowel syndrome (IBS) according to the Pediatric Gastrointestinal Symptoms Rome IV criteria.
The exclusion criteria are on the listing.
What it tests, as registered
Psyllium Husk; Conventional therapy group
Registered summary
Children aged 6 to 17 years with IBS will be randomly assigned to either receive psyllium husk supplementation in addition to usual care or receive usual care alone. The study will compare gastrointestinal symptoms, quality of life, and gut microbiota between the two groups.