Prunes (Dried Plums) trials recruiting now

4 registrations that name prunes as a study arm and are recruiting or about to, as ClinicalTrials.gov listed them on Oct 20, 2026. Read each listing for its full criteria and current status.

Kymata never assesses eligibility. Each listing names its own criteria; only its study team can say whether someone can join. Trial doses are given under the trial's monitoring and are not a schedule for anyone outside it.

Filter 4 registrations

Status

3US sites across 3 states

All 4 registrations

RecruitingNCT06184646

Elucidating the Minimal Effective Dose of Prunes for Bone Health in Postmenopausal Women

  • No phase
  • San Diego State University
  • About 200 people
  • Started Mar 15, 2024

In plain words A study of prunes in female participants of any age, run by San Diego State University. It plans to enroll about 200 people at 1 US site.

Who it lists and where

Who the trial lists, as registered

Lists female participants of any age. Conditions: Bone Disease, Metabolic.

  • Postmenopausal
  • BMD t-score is between 0.5 and 2 SD below the mean
  • Not on hormone replacement therapy (HRT) and/or other pharmacological agents known to affect bone for at least three months prior to initiation of the study

The exclusion criteria are on the listing.

What it tests, as registered

Prune

Registered summary

The objective of this study is to examine if calcium and vitamin D supplements and/or prune can prevent bone loss in postmenopausal women.

Where, as registered

1 US site in 1 state.

RecruitingNCT07120997

Prunes Preventing Bone Loss in Perimenopause

  • No phase
  • Penn State University
  • About 124 people
  • Started Dec 11, 2025

In plain words A study of prunes in female participants 44 to 55, run by Penn State University. It plans to enroll about 124 people at 1 US site.

Who it lists and where

Who the trial lists, as registered

Lists female participants 44 to 55; healthy volunteers accepted. Conditions: Perimenopausal Bone Loss.

  • Age 44 to 55 years
  • Not severely obese (BMI <35 kg/m\^2)
  • Healthy (determined by a screening questionnaire, physical and medical history by a certified nurse practitioner, complete metabolic panel, and complete blood count)
  • Willing to include prunes in their daily diet

5 more inclusion criteria and the exclusion criteria are on the listing.

What it tests, as registered

Prunes; Calcium supplement; Vitamin D Supplement

Registered summary

Dietary interventions of prune consumption during the transmenopausal period are innovative methods to prevent bone loss. Modern medicine does not intervene to prevent or attenuate this highly vulnerable period of bone loss which, if successfully attenuated, can potentially prevent/delay osteoporosis in women. The transmenopausal period represents an opportunistic window for the study because bone loss is at its greatest at this time, with females losing as much as 6-7% of bone. The full summary is on the listing.

Where, as registered

1 US site in 1 state.

RecruitingNCT07222111

Prebiotics (Dried Plum) and Immune Function in Postmenopausal Women

  • No phase
  • Indiana University
  • About 30 people
  • Started Sep 2, 2025

In plain words A study of prunes in female participants 60 to 75, run by Indiana University. It plans to enroll about 30 people at 1 US site.

Who it lists and where

Who the trial lists, as registered

Lists female participants 60 to 75; healthy volunteers accepted. Conditions: T Cell Response to Dried Plum; Vitamin D Influence on Immune Response; Dried Plum and Immune Function.

  • women 60-75 years of age at the start of the study;
  • 12 or more consecutive months without a menstrual period;
  • willing to include dried plums in their daily diet and collect fecal samples at four time points;
  • ambulatory without assistance;

1 more inclusion criterion and the exclusion criteria are on the listing.

What it tests, as registered

Dried plums

Registered summary

Prior studies have shown that dietary supplementation with dried plums (also known as prunes) reduces bone loss in postmenopausal women. The purpose of this clinical trial is to understand how dried plums mediate their effects on bone. The main questions the study will answer are: 1. Does adding dried plums to the diet alter immune cell function? 2. Does dried plum alter gut microbes? 3. Does a person's vitamin D status influence this response? Researcher will compare the response following consumption of the normal diet to supplementing the diet with dried plums. Participant will: 1. The full summary is on the listing.

Where, as registered

1 US site in 1 state.

RecruitingNCT06963125

The Effects of Prune Juice on Bowel Movement Patterns, Constipation Symptoms, and Quality of Life

  • No phase
  • Dalin Tzu Chi General Hospital
  • About 90 people
  • Started May 26, 2025

In plain words A study of prunes in people 65 to 100, run by Dalin Tzu Chi General Hospital. It plans to enroll about 90 people at 1 site, none in the US.

Who it lists and where

Who the trial lists, as registered

Lists people 65 to 100. Conditions: Constipation in Older Adults; Functional Constipation in Elderly.

  • Older adults aged 65 to 100 years
  • Cognitively aware and able to express their opinions
  • Diagnosed with functional constipation

The exclusion criteria are on the listing.

What it tests, as registered

Low-Dose Prune Juice; Medium-Dose Prune Juice; High-Dose Prune Juice

Registered summary

This study investigates the effects of different prune juice dosages on bowel movement patterns, constipation symptoms, and quality of life in older adults. Using a factorial experimental design, 90 participants aged 65 to 100 with functional constipation will be randomly assigned to receive 100 mL, 150 mL, or 200 mL of prune juice daily for four weeks. The study aims to determine a safe and effective dosage for constipation management, offering a non-pharmacological approach to improving bowel health in older adults.

Where, as registered

No US site; Taiwan (1).

ClinicalTrials.gov lists 10 open registrations for this search, including ones where prunes is not a study arm or that are past the 4 we keep. Search them on ClinicalTrials.gov (opens in new tab).

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