Pomegranate trials recruiting now

6 registrations that name pomegranate as a study arm and are recruiting or about to, as ClinicalTrials.gov listed them on Oct 20, 2026. Read each listing for its full criteria and current status.

Kymata never assesses eligibility. Each listing names its own criteria; only its study team can say whether someone can join. Trial doses are given under the trial's monitoring and are not a schedule for anyone outside it.

Filter 6 registrations

Status

Phase

4US sites across 2 states

All 6 registrations

RecruitingNCT07115862

Effects of Pomegranate Juice on Ulcerative Colitis

  • No phase
  • University of California, Los Angeles
  • About 30 people
  • Started Oct 15, 2025

In plain words A study of pomegranate in people 18 and older, run by University of California, Los Angeles. It plans to enroll about 30 people at 2 US sites.

Who it lists and where

Who the trial lists, as registered

Lists people 18 and older. Conditions: Ulcerative Colitis (Disorder).

  • • Adults ≥ 18 yo
  • Following a low-polyphenol and fiber diet (< 3 servings of fruits/vegetables per day)
  • Mild-to-moderate UC at the time of screening (2 ≤ partial Mayo scores ≤ 5)
  • Supportive evidence of active inflammation (hsCRP >1 mg/L, fecal calprotectin >50 µg/g stool, or abnormal lower endoscopy) in individuals with biopsy-proven UC

4 more inclusion criteria and the exclusion criteria are on the listing.

What it tests, as registered

pomegranate juice -> habitual diet; habitual diet -> pomegranate juice

Registered summary

The purpose of this study is to determine whether consumption of 237 ml of pomegranate juice daily for 8 weeks will: 1. lower inflammation (in the gut as well as generally in the body) and improve your overall quality of life 2. affect the microbes living in the gut (gut microbiota)

Where, as registered

2 US sites in 1 state.

RecruitingNCT04985630

The Mitopure Challenge to Detect Levels of Urolithin A in Dried Blood Spots

  • No phase
  • Amazentis SA
  • About 250 people
  • Started Aug 30, 2021

In plain words A study of pomegranate in people 18 to 80, run by Amazentis SA. It plans to enroll about 250 people at 1 US site.

Who it lists and where

Who the trial lists, as registered

Lists people 18 to 80; healthy volunteers accepted. Conditions: Healthy Aging; Healthy; Healthy Diet.

  • Males and females 18 to 80 years of age;
  • Is in general good health, as determined by the research team;
  • Willingness to consume the investigation product, complete questionnaires and to complete the study;
  • Have given voluntary, electronic, informed consent to be a participant in the study.

The exclusion criteria are on the listing.

What it tests, as registered

Mitopure; Pomegranate Juice

Registered summary

Open labelled, virtual home based study to assess the test repeatability and the failure/rejection rate of the samples collected at home by participants.

Where, as registered

1 US site in 1 state.

RecruitingNCT06069531

Effect of Lactobacillus Johnsonii or White Pomegranate Extract on the Vaginal Health

  • No phase
  • Chung Shan Medical University
  • About 150 people
  • Started Apr 4, 2022

In plain words A study of pomegranate in female participants 20 to 45, run by Chung Shan Medical University. It plans to enroll about 150 people at 1 site, none in the US.

Who it lists and where

Who the trial lists, as registered

Lists female participants 20 to 45. Conditions: Vaginitis Bacterial; Inflammation, Ear.

  • Females aged 20-45
  • Nugent score ≥ 4
  • Menstrual cycle of 28-60 days

The exclusion criteria are on the listing.

What it tests, as registered

Lactobacillus johnsonii, Placebo Comparator: White pomegranate extract

Registered summary

The goal of this clinical trial is to explore the effect of Lactobacillus johnsonii and white pomegranate extract on female bacterial status, it aims to answer are: * Evaluate Lactobacillus johnsonii TCI250 probiotics or white pomegranate extract in regulating female vaginal bacteria and improving vaginal health. * Evaluate Lactobacillus johnsonii TCI250 probiotics or white pomegranate extract in regulating inflammation. The full summary is on the listing.

Where, as registered

No US site; Taiwan (1).

RecruitingNCT06550167

Neuroprotective Effect of (Nano PSO), in Patients Who Used to Consume Psychoactive Substances

  • No phase
  • Distribuidora Biolife SA de CV
  • About 80 people
  • Started Mar 15, 2024

In plain words A study of pomegranate in male participants 18 to 50, run by Distribuidora Biolife SA de CV. It plans to enroll about 80 people at 1 site, none in the US.

Who it lists and where

Who the trial lists, as registered

Lists male participants 18 to 50. Conditions: Addiction;Drug(S);LSD; Neuroprotective.

  • Patients who are multiple users of methamphetamines, cocaine, and cannabis with or without alcohol and tobacco, and have a history of at least 3 years of consumption.
  • Patients who accept informed consent to participate in the protocol.
  • Male gender.
  • Age between 18-50 years in the withdrawal phase currently in residential treatment

The exclusion criteria are on the listing.

What it tests, as registered

Nano-PSO, Pomegranate seed oil (omega-5); PLACEBO

Registered summary

Addiction problems to psychoactive substances are becoming more frequent, which implies a serious health problem, with social, family and work repercussions. Participants with chronic consumption present important degeneration processes mediated by Neuroinflammation, oxidative stress and excitotoxicity. At the moment there is no effective treatment that can reduce the damage. The effectiveness of Omega 5 has been demonstrated in different disorders of the nervous system; However, very little has been elucidated about the mechanisms of regulation and activation in consumer patients. The full summary is on the listing.

Where, as registered

No US site; Mexico (1).

RecruitingNCT06520878

Impact of NANO-PSO on Cognition in Older Adults with Mild to Moderate Cognitive Impairment

  • Phase 2
  • Distribuidora Biolife SA de CV
  • About 60 people
  • Starts Feb 12, 2025 (estimated)

In plain words A Phase 2 study of pomegranate in people 60 and older, run by Distribuidora Biolife SA de CV. It plans to enroll about 60 people at 1 site, none in the US.

Who it lists and where

Who the trial lists, as registered

Lists people 60 and older. Conditions: Cognition.

  • Patients attended at the Hospital Español.
  • Patients of any gender who are 60 years or older.
  • Patients presenting with mild to moderate cognitive impairment.
  • Meet the diagnostic criteria for \&#34;probable dementia\&#34; of the National Institute on Aging and the Alzheimer's Association (NIA-AA) (2011).

6 more inclusion criteria and the exclusion criteria are on the listing.

What it tests, as registered

NANO-PSO (pomegranate seed oil); Placebo

Registered summary

The objective of this randomized, triple-blind, placebo-controlled clinical trial is to compare NANO-PSO therapy against placebo in improving cognitive abilities in older adults with mild to moderate non-vascular cognitive impairment over six months of treatment. The full summary is on the listing.

Where, as registered

No US site; Mexico (1).

Not yet recruitingNCT07678567

Pomegranate Dietary Supplements in AUD and ALD

  • Observational
  • University of Louisville
  • About 144 people
  • Starts Jan 1, 2027 (estimated)

In plain words An observational study of pomegranate in people 18 and older, run by University of Louisville. It plans to enroll about 144 people at 1 US site.

Who it lists and where

Who the trial lists, as registered

Lists people 18 and older; healthy volunteers accepted. Conditions: Alcohol Use Disorder; Alcohol-associated Liver Disease; Alcoholic Cirrhosis; Healthy.

What it tests, as registered

Pomegranate Dietary Ssupplement

Registered summary

The goal of this project is to determine an individual's ability to generate active gut microbial metabolites called urolithins upon consumption of pomegranate dietary supplements. Recent publications have reported that urolithins are the major active metabolites responsible for the beneficial effects of eating pomegranates, berries, or walnuts. However, the production of urolithins from the parent compound ellagic acid (EA) is dependent upon the presence of certain bacteria in the human gut. The full summary is on the listing.

Where, as registered

1 US site in 1 state.

ClinicalTrials.gov lists 12 open registrations for this search, including ones where pomegranate is not a study arm or that are past the 6 we keep. Search them on ClinicalTrials.gov (opens in new tab).

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