Plant Stanol Esters and Preventing Asthma Symptoms
In plain words A study of phytosterols in people 18 to 70, run by Maastricht University Medical Center. It plans to enroll about 160 people at 1 site, none in the US.
Who it lists and where
Who the trial lists, as registered
Lists people 18 to 70. Conditions: Asthma, Allergic; Cardiovascular Diseases.
- Diagnosed with allergic asthma (GINA step 1-4) which is in a stable phase at the moment of inclusion (defined as no changes in asthma control and lung function in (at least) the past three months)
- Have been treated with prescribed asthma medication for at least one year
- Aged 18-70 years old
- BMI between 20 and 35 kg/m2
3 more inclusion criteria and the exclusion criteria are on the listing.
What it tests, as registered
Soft chews containing 0.5g plant stanols (delivered as plant stanol esters); Placebo soft chew
Registered summary
Plant stanols are known to lower low-density lipoprotein cholesterol. However, studies have suggested that these compounds also influence the immune system. Asthmatic responses are predominantly T helper (Th)2 cell dependent, while plant stanols were previously found to activate Th1 cells and shift the immune response away from the Th2 cell dominant asthmatic response. The full summary is on the listing.
Where, as registered
No US site; Netherlands (1).