2 registrations that name lion's mane mushroom as a study arm and are recruiting or about to, as ClinicalTrials.gov listed them on Oct 20, 2026. Read each listing for its full criteria and current status.
Kymata never assesses eligibility. Each listing names its own criteria; only its study team can say whether someone can join. Trial doses are given under the trial's monitoring and are not a schedule for anyone outside it.
Filter 2 registrations
Status
Phase
1US sites across 1 state
1
2 to 4
5 to 19
20 or more
All 2 registrations
RecruitingNCT06870136
Study Evaluating the Quality and Effects of Lion's Mane Product on Cognitive Health
Observational
M2 Ingredients
About 150 people
Started Feb 21, 2025
In plain words An observational study of lion's mane mushroom in people 40 to 75, run by M2 Ingredients. It plans to enroll about 150 people at 1 US site.
Who it lists and where
Who the trial lists, as registered
Lists people 40 to 75. Conditions: Cognitive Decline.
Individuals 40-75 years old, inclusive
Has self-reported concerns with reduced memory, focus and cognitive decline
Cognitive Failures Questionnaire score of mild to moderate at screening
Interested in understanding more about their cognitive health and have chosen have chosen to use the study product
10 more inclusion criteria and the exclusion criteria are on the listing.
What it tests, as registered
Lion's Mane Study Product
Registered summary
The rationale for this study is to observe differences in cognitive health outcomes such as short term memory and simple reaction time between a consumer-grade and commercially available Lion's mane mushroom product and a placebo control group. Additionally, the study aims to evaluate the impact of the product on cognitive function, mood, focus, motivation, sleep quality, and stress. A consumer-driven, decentralized observational clinical research study is therefore well-suited for evaluating the impact of this product in this population. The full summary is on the listing.
Where, as registered
1 US site in 1 state.
Not yet recruitingNCT07759687
Lion's Mane Dosing on Attention and Mood
No phase
Northumbria University
About 24 people
Starts Aug 2026 (estimated)
In plain words A study of lion's mane mushroom in people 18 to 45, run by Northumbria University. It plans to enroll about 24 people at 1 site, none in the US.
Who it lists and where
Who the trial lists, as registered
Lists people 18 to 45; healthy volunteers accepted. Conditions: Attention.
Participants must self-assess themselves as being in good health
Participants must be aged 18 to 45 at the time of giving consent
Understand and are willing to participate in all scheduled visits and to adhere to the trial procedures outlined in the subject information sheet
Are fluent in English (equivalent to IELTS Level 6)
The exclusion criteria are on the listing.
What it tests, as registered
Lion's Mane fruiting bodies extract; Placebo
Registered summary
The primary purpose of the research is to evaluate in healthy adults the time course effects of varying dosages of Lion's mane mushroom on attention and mood.
Where, as registered
No US site; United Kingdom (1).
ClinicalTrials.gov lists 4 open registrations for this search, including ones where lion's mane mushroom is not a study arm or that are past the 2 we keep. Search them on ClinicalTrials.gov (opens in new tab).