3 registrations that name L-Methionine as a study arm and are recruiting or about to, as ClinicalTrials.gov listed them on Oct 20, 2026. Read each listing for its full criteria and current status.
Kymata never assesses eligibility. Each listing names its own criteria; only its study team can say whether someone can join. Trial doses are given under the trial's monitoring and are not a schedule for anyone outside it.
Filter 3 registrations
Status
Phase
1US sites across 1 state
1
2 to 4
5 to 19
20 or more
All 3 registrations
RecruitingNCT07628634
Feasibility Study on the Effect of a Methionine-Reduced Diet on Serum Levels in Pts w/ Solid Tumors
Early phase 1
University of California, Irvine
About 25 people
Started May 1, 2026
In plain words An early phase 1 study of L-Methionine in people 18 and older, run by University of California, Irvine. It plans to enroll about 25 people at 1 US site.
Diagnosis: Has a diagnosis of metastatic, recurrent, or unresectable solid tumors.
Life Expectancy: Subjects must have an expected life expectancy of at least 3 months.
Performance Status: Subjects must have an ECOG performance status of 0-2.
7 more inclusion criteria and the exclusion criteria are on the listing.
What it tests, as registered
Methionine-Reduced Diet
Registered summary
This is a pilot clinical trial determining the effect of a Methionine-reduced diet on serum levels in subjects with solid tumors. These are subjects who will receive systemic standard of care cancer therapy.
Where, as registered
1 US site in 1 state.
Not yet recruitingNCT07465367
Methionine for CaPhos Stone
No phase
Ryan L Steinberg
About 15 people
Starts Apr 1, 2026 (estimated)
In plain words A study of L-Methionine in people 18 to 90, run by Ryan L Steinberg. It plans to enroll about 15 people and lists no sites yet.
Who it lists and where
Who the trial lists, as registered
Lists people 18 to 90. Conditions: Calcium Phosphate Kidney Stones.
Any patient, aged 18-90 and not incarcerated, under the care of a urologist at UIHC, with a history of kidney stones with >60% calcium phosphate composition, prior 24 hour urine collection showing a urine pH of >6.1, internet access to…
The exclusion criteria are on the listing.
What it tests, as registered
L-Methionine
Registered summary
Some kidney stones including calcium phosphate and struvite stones form in vary alkaline urine (high pH). Currently available medication for stone prevention, namely citrate supplementation, can lead to even higher pH levels and promote stone formation. Multiple prior studies have looked at ways to acidify the urine to reduce the risk of recurrent stone formation. Ascorbic acid has been evaluated but showed no reduction in urinary pH. Ammonium chloride has shown to be effective but poorly tolerated (GI upset) at higher doses and thus is not recommended. The full summary is on the listing.
Where, as registered
No sites listed yet.
Not yet recruitingNCT06184984
Metabolic Availability of Methionine in Mung Beans
No phase
Food and Nutrition Research Institute, Philippines
About 6 people
Starts Apr 2025 (estimated)
In plain words A study of L-Methionine in female participants 19 to 40, run by Food and Nutrition Research Institute, Philippines. It plans to enroll about 6 people at 1 site, none in the US.
Who it lists and where
Who the trial lists, as registered
Lists female participants 19 to 40; healthy volunteers accepted. Conditions: Healthy Women of Child Bearing Potential.
Non-pregnant
Non-lactating
Stable body weight
Healthy, with no known clinical condition that would affect protein or AA metabolism, e.g. Diabetes
1 more inclusion criterion and the exclusion criteria are on the listing.
What it tests, as registered
Metabolic availability of methionine in mung beans
Registered summary
The goal of this study is to determine the protein quality of Philippine mung beans. The main objective of this study is to determine the metabolic availability of methionine in mung beans that the body can use. We will test the mung beans by studying them after cooking them as sauté. This research is being done in order to bridge the gap between knowledge of protein requirement and the amount of food needed to meet that requirement. Results from this study will be important for recommendations guiding food choices of mung beans as a major protein source in the diet. The full summary is on the listing.