5 registrations that name kefir as a study arm and are recruiting or about to, as ClinicalTrials.gov listed them on Oct 20, 2026. Read each listing for its full criteria and current status.
Kymata never assesses eligibility. Each listing names its own criteria; only its study team can say whether someone can join. Trial doses are given under the trial's monitoring and are not a schedule for anyone outside it.
Filter 5 registrations
Status
Phase
All 5 registrations
RecruitingNCT06695221
Improving Health Outcomes With Kefir
No phase
University of Alberta
About 156 people
Started Mar 24, 2026
In plain words A study of kefir in people 24 to 70, run by University of Alberta. It plans to enroll about 156 people at 1 site, none in the US.
Who it lists and where
Who the trial lists, as registered
Lists people 24 to 70. Conditions: Systemic Inflammatory Response; Diabetes Mellitus, Type 2; Cardiovascular Diseases.
females and males (24-70 years old) living in Edmonton (or Edmonton area/driving distance);
overweight or obesity (BMI >25 Caucasian, >23 Asian);
at higher risk of T2D (fasting blood glucose ≥ 5.6 - 6.9 mmol/L or/and HbA1C ≥ 5.5 - 6.4%); or
with diagnosis of T2D (fasting blood glucose ≥ 7.0 mmol/L or/and HbA1C ≥ 6.5%).
The exclusion criteria are on the listing.
What it tests, as registered
Traditional Kefir; Milk (placebo)
Registered summary
The purpose of the study is to ascertain whether traditional kefir not only enhances vascular health but also contributes to improved immune outcomes in both male and female participants at higher risk or living with Type 2 Diabetes (T2D) after 12 weeks of treatment.
Where, as registered
No US site; Canada (1).
RecruitingNCT06900881
Role of Kefir Mouth Wash in Oral Health Status Amelioration
Phase 2 and 3
Al-Mustansiriyah University
About 60 people
Started Apr 6, 2025
In plain words A Phase 2 and 3 study of kefir in people 18 to 28, run by Al-Mustansiriyah University. It plans to enroll about 60 people at 1 site, none in the US.
Who it lists and where
Who the trial lists, as registered
Lists people 18 to 28; healthy volunteers accepted. Conditions: Plaque Induced Gingivitis; Halitosis; Oral Disease.
Age range 18-28 years.
Systemically healthy people without a history of chronic illness.
The present research aims to evaluate the efficiency of kefir mouthwash in enhancing oral health status by employing an in vivo experimental approach. Specifically, the study will assess how kefir mouthwash influences key oral health indicators, including gingival inflammation, plaque development, oral hygiene status, and halitosis. The study will be conducted over a 28-day period, with follow-up assessments every 14 days. The study will include systemically healthy adults with moderate gingivitis. The full summary is on the listing.
In plain words A study of kefir in female participants 19 and older, run by University of New Brunswick. It plans to enroll about 60 people at 1 site, none in the US.
Who it lists and where
Who the trial lists, as registered
Lists female participants 19 and older; healthy volunteers accepted. Conditions: Gestational Diabetes Mellitus (GDM); Blood Glucose; Insulin Resistance, Diabetes; Gut Microbiome; Gut Metabolites.
Pregnant individual with a singleton pregnancy
19 years and older of age
Gestational age 14,3 weeks or less at enrolment
Able and willing to attend four in-person study visits at the PEADS Laboratory: baseline, 18-20 weeks' gestation, 26-28 weeks' gestation, and 1 month postpartum
11 more inclusion criteria and the exclusion criteria are on the listing.
What it tests, as registered
Kefir
Registered summary
Pregnancy is a critical window for metabolic health, and early changes in blood sugar regulation can increase the risk of gestational diabetes mellitus (GDM), which affects both maternal and infant health. At the same time, the maternal gut microbiome changes throughout pregnancy and may play a role in glucose metabolism and insulin resistance. Kefir, a fermented milk drink containing beneficial bacteria and yeasts, may be a simple dietary strategy to support metabolic health during pregnancy, but its role in preventing GDM has not been well studied. The full summary is on the listing.
Where, as registered
No US site; Canada (1).
RecruitingNCT07071181
Effects of Milk-based Drinks on Gut Microbiome, Sleep and Cardiometabolic Markers
No phase
Sheffield Hallam University
About 40 people
Starts Aug 2025 (estimated)
In plain words A study of kefir in people 40 to 70, run by Sheffield Hallam University. It plans to enroll about 40 people at 2 sites, none in the US.
Who it lists and where
Who the trial lists, as registered
Lists people 40 to 70; healthy volunteers accepted. Conditions: Sleep; Cardiovascular Diseases; Gut Microbiome; Cognitive Function and Mood; LDL Cholesterol.
Aged 40-70 years old
Suffer with poor sleep (measured using the PIttsburg Sleep Quality Index with a score > 5)
BMI in range of 25-35 kg/m2
Willingness to consume each study drink daily for 4 weeks and attend the laboratory on 4 separate occasions
1 more inclusion criterion and the exclusion criteria are on the listing.
What it tests, as registered
Original flavour kefir; Milk
Registered summary
The purpose of this study is to evaluate the effects of kefir on gastrointestinal health, sleep quality, and biochemical parameters in adults who have sleep problems. Further measurements of cognitive function, arterial stiffness and blood pressure will also be assessed. The following questions will be addressed during the study: 1. What effect does repeated ingestion of kefir have on the gut microbiome and can this positively influence sleep performance (quality and duration) in adults with sleep problems? 2. The full summary is on the listing.
Where, as registered
No US site; United Kingdom (2).
Not yet recruitingNCT07777666
Effects of Kefir on Celiac Disease
No phase
University Maribor
About 30 people
Starts Sep 30, 2026 (estimated)
In plain words A study of kefir in people 18 and older, run by University Maribor. It plans to enroll about 30 people at 1 site, none in the US.
Who it lists and where
Who the trial lists, as registered
Lists people 18 and older. Conditions: Celiac Disease.
Adults aged 18 years or older with a confirmed diagnosis of celiac disease.
Following a strict gluten-free diet.
The exclusion criteria are on the listing.
What it tests, as registered
kefir
Registered summary
This study will investigate whether regular consumption of kefir can reduce gastrointestinal symptoms and improve quality of life in adults with celiac disease who follow a strict gluten-free diet. The study will use a randomized cross-over design in which participants will consume kefir during one study period and continue their usual diet without kefir during another period.