Human Milk Oligosaccharides (HMOs) trials recruiting now

2 registrations that name human Milk Oligosaccharides as a study arm and are recruiting or about to, as ClinicalTrials.gov listed them on Oct 20, 2026. Read each listing for its full criteria and current status.

Kymata never assesses eligibility. Each listing names its own criteria; only its study team can say whether someone can join. Trial doses are given under the trial's monitoring and are not a schedule for anyone outside it.

Filter 2 registrations

Status

Phase

1US sites across 1 state

All 2 registrations

RecruitingNCT06631937

HMOs on Infant Gut Microbiota Modulation and Development of the Immune System in Healthy Infants

  • No phase
  • University of Aarhus
  • About 334 people
  • Started Nov 5, 2024

In plain words A study of human Milk Oligosaccharides in people 0 days to 28 days, run by University of Aarhus. It plans to enroll about 334 people at 2 sites, none in the US.

Who it lists and where

Who the trial lists, as registered

Lists people 0 days to 28 days; healthy volunteers accepted. Conditions: Healthy Infants.

  • All infants which parents has decided mode of feeding

The exclusion criteria are on the listing.

What it tests, as registered

Human Milk Oligosaccharides; Placebo

Registered summary

The goal of this clinical trial is to learn how a mixture of human milk oligosaccharides impacts the development of the infant microbiota, the immune maturation and how the interaction between the microbiota and immune maturation may impact both short and long term health of the infant. The full summary is on the listing.

Where, as registered

No US site; Denmark (2).

Not yet recruitingNCT06791993

Impact of Probiotics on Gut Microbiome During Antibiotic Prophylaxis in Elective Orthopedic Surgery

  • Phase 4
  • Acibadem Maslak Hospital
  • About 60 people
  • Starts Feb 1, 2025 (estimated)

In plain words A Phase 4 study of human Milk Oligosaccharides in people 18 to 65, run by Acibadem Maslak Hospital. It plans to enroll about 60 people at 6 sites, 1 of them in the US.

Who it lists and where

Who the trial lists, as registered

Lists people 18 to 65. Conditions: Dysbiosis; Gut -microbiota; Microbiome Analysis; Probiotic; Antibiotic Prophylaxis.

  • Adults aged between 18 and 65 years
  • Scheduled for elective low-risk orthopedic surgery (carpal tunnel release, A1 pulley release, knee arthroscopic surgery).

The exclusion criteria are on the listing.

What it tests, as registered

Placebo Capsule; Probiotic with Human Milk Oligosaccharides (HMO)

Registered summary

This study aims to evaluate whether probiotics can help maintain a healthy gut microbiome in patients receiving prophylactic antibiotics during elective orthopedic surgery. Antibiotics, while effective in preventing infections, can disrupt the balance of gut bacteria, leading to dysbiosis. The study hypothesizes that the use of probiotics during the perioperative period can prevent or reduce this disruption, supporting gut health and overall well-being. The full summary is on the listing.

Where, as registered

1 US site in 1 state; also Turkey (Türkiye) (4), Thailand (1).

ClinicalTrials.gov lists 11 open registrations for this search, including ones where human Milk Oligosaccharides is not a study arm or that are past the 2 we keep. Search them on ClinicalTrials.gov (opens in new tab).

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