Horse Chestnut trials recruiting now

1 registration that name horse Chestnut as a study arm and are recruiting or about to, as ClinicalTrials.gov listed them on Oct 20, 2026. Read each listing for its full criteria and current status.

Kymata never assesses eligibility. Each listing names its own criteria; only its study team can say whether someone can join. Trial doses are given under the trial's monitoring and are not a schedule for anyone outside it.

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Status

All 1 registrations

RecruitingNCT07244029

Aescin-Based Herbal Extract (Reparil) for Postoperative Sequelae After Mandibular Third Molar Surgery

  • No phase
  • Oman Medical Speciality Board
  • About 100 people
  • Started Jan 1, 2026

In plain words A study of horse Chestnut in people 18 to 40, run by Oman Medical Speciality Board. It plans to enroll about 100 people at 1 site, none in the US.

Who it lists and where

Who the trial lists, as registered

Lists people 18 to 40; healthy volunteers accepted. Conditions: Postoperative Pain; Facial Swelling; Trismus.

  • Patients indicated for surgical removal of impacted mandibular third molars according to National Institute for Health and Care Excellence (NICE) guidelines.

The exclusion criteria are on the listing.

What it tests, as registered

Escin; Ibuprofen 400 mg

Registered summary

This randomized, single-blind, controlled clinical trial aims to evaluate the efficacy and safety of Aescin-based herbal extract (Reparil®) compared with Ibuprofen in managing postoperative sequelae following surgical removal of impacted mandibular third molars. A total of 100 participants aged 18-40 years will be enrolled at the Dental Center, Medical City Hospital for Military and Security Services (MCMSS), Al Khoud, Oman. The full summary is on the listing.

Where, as registered

No US site; Oman (1).

ClinicalTrials.gov lists 5 open registrations for this search, including ones where horse Chestnut is not a study arm or that are past the 1 we keep. Search them on ClinicalTrials.gov (opens in new tab).

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