7 registrations that name green tea extract as a study arm and are recruiting or about to, as ClinicalTrials.gov listed them on Oct 20, 2026. Read each listing for its full criteria and current status.
Kymata never assesses eligibility. Each listing names its own criteria; only its study team can say whether someone can join. Trial doses are given under the trial's monitoring and are not a schedule for anyone outside it.
Filter 7 registrations
Status
Phase
2US sites across 2 states
1
2 to 4
5 to 19
20 or more
All 7 registrations
RecruitingNCT06531863
Curcumin and EGCG Supplementation to Improve Serum BDNF and Mood Disturbance
Early phase 1
Auburn University
About 64 people
Started Sep 30, 2024
In plain words An early phase 1 study of green tea extract in people 18 to 50, run by Auburn University. It plans to enroll about 64 people at 1 US site.
Who it lists and where
Who the trial lists, as registered
Lists people 18 to 50; healthy volunteers accepted. Conditions: Mood Disturbance.
Adults age 18-50
Depression subscale score of >9/21 on the DASS-21
No change in medications or supplements over the past 3 months
Can read and speak English
The exclusion criteria are on the listing.
What it tests, as registered
Curcumin; Epigallocatechin Gallate; Placebo
Registered summary
The goal of this randomized placebo controlled trial is to examine mood disturbance and serum brain derived neurotrophic factor (BDNF) in people (age 18-50) with DASS-21 subscale scores \>9. The main questions it aims to answer are: Does curcumin and EGCG supplementation improve mood disturbance symptomology? Does curcumin and EGCG supplementation increase serum BDNF? Researchers will compare intervention versus placebo. Participants will consume an 8-week supplement of both: * 1,330mg/day curcumin * 350mg/day epigallocatechin gallate (EGCG)
Where, as registered
1 US site in 1 state.
RecruitingNCT06015022
EGCG for Hepatocellular Carcinoma Chemoprevention
Phase 2
University of Texas Southwestern Medical Center
About 60 people
Started Sep 1, 2024
In plain words A Phase 2 study of green tea extract in people 18 and older, run by University of Texas Southwestern Medical Center. It plans to enroll about 60 people at 1 US site.
Who it lists and where
Who the trial lists, as registered
Lists people 18 and older. Conditions: Cirrhosis, Liver.
6 more inclusion criteria and the exclusion criteria are on the listing.
What it tests, as registered
Epigallocatechin gallate (EGCG); Placebo
Registered summary
This phase II trial tests epigallocatechin gallate (EGCG) for its efficacy and safety in preventing development of hepatocellular carcinoma (HCC) in patients with liver cirrhosis.
Where, as registered
1 US site in 1 state.
RecruitingNCT07094035
The Beneficial Effects on the Intestinal Function of a Food Supplement Based on an Extract of Green Tea and a Pool of Probiotics in Subjects With Irritable Bowel Syndrome With Predominance of Constipation
No phase
Adamas Biotech S.r.l.
About 64 people
Started Jul 30, 2025
In plain words A study of green tea extract in people 18 to 70, run by Adamas Biotech S.r.l.. It plans to enroll about 64 people at 1 site, none in the US.
Who it lists and where
Who the trial lists, as registered
Lists people 18 to 70. Conditions: IBS, Constipation Predominant.
aged between 18 and 70 years
able to understand and sign informed consent
HIV negative test
negative pregnancy test
9 more inclusion criteria and the exclusion criteria are on the listing.
What it tests, as registered
food supplement based on a mixture of green tea extract and a pool of probiotics.; Placebo
Registered summary
The study will aim to evaluate the effectiveness of the use of a food supplement, based on a green tea extract (Camellia sinensis (L.) Kuntze - folium) and a pool of probiotics (L. plantarum, L. rhamnosus and B. animalis subsp. lactis), in the management of gastrointestinal distress in the general population and in subjects with IBS in the predominant form of IBS-C, with an impact on quality of life. The full summary is on the listing.
Where, as registered
No US site; Italy (1).
RecruitingNCT05448365
Vitamin D, Epigallocatechin Gallate, D-chiro-inositol and Vitamin B6 in Uterine Fibroid
No phase
Lo.Li.Pharma s.r.l
About 60 people
Started Jul 1, 2022
In plain words A study of green tea extract in female participants 30 to 40, run by Lo.Li.Pharma s.r.l. It plans to enroll about 60 people at 2 sites, none in the US.
The study will evaluate the impact on uterine fibroids' volume of a combination of natural molecules including Epigallocatechin gallate, Vitamin D, D-chiro-inositol and Vitamin B6. The patients will be evaluated at baseline and after three months of treatment with placebo or product.
Where, as registered
No US site; Italy (2).
RecruitingNCT04871412
The Thoracic Peri-Operative Integrative Surgical Care Evaluation Trial - Stage III
Phase 3
Ottawa Hospital Research Institute
About 20 people
Started Apr 4, 2022
In plain words A Phase 3 study of green tea extract in people 18 and older, run by Ottawa Hospital Research Institute. It plans to enroll about 20 people at 2 sites, none in the US.
Who it lists and where
Who the trial lists, as registered
Lists people 18 and older. Conditions: Lung Cancer; Gastric Cancer; Esophageal Cancer.
Adults eligible for complete resection of lung, gastric or esophageal cancer
The exclusion criteria are on the listing.
What it tests, as registered
Vitamin D3 Drops; Coriolus Versicolor; Trident SAP 66:33 Lemon; Probiotic Pro12; Provitalix Pure Whey Protein; Theracurmin 2X; Green Tea Extract; Nutrition Recommendations; Physical Activity Recommendations; Psychological Recommendations
Registered summary
Despite enormous advances in thoracic surgery and oncology, two critical issues concern patients undergoing curative-intent surgery for lung, gastric and esophageal cancer: first, a majority (\~60%) of patients experience minor and major adverse events occurring during and in the days following surgery; second, patients worry about the significant risk of cancer recurrence and mortality months to years after surgery. These issues, combined with side effects of chemotherapy and radiation, have detrimental effects on health-related quality of life (HRQoL). The full summary is on the listing.
Where, as registered
No US site; Canada (2).
Not yet recruitingNCT07697196
Effect of EGCG, Folic Acid, Vitamin B12 and Hyaluronic Acid on HPV DNA Integration
No phase
IRCCS San Raffaele
About 42 people
Starts Jul 2026 (estimated)
In plain words A study of green tea extract in female participants 25 and older, run by IRCCS San Raffaele. It plans to enroll about 42 people at 1 site, none in the US.
Who it lists and where
Who the trial lists, as registered
Lists female participants 25 and older. Conditions: HPV Infection; HPV Integration; HPV Disease; HPV Genital Infection; HPV Persistence; Low Grade Squamous Intraepithelial Lesions of the Cervix.
Age ≥ 25 years old
Positive HPV DNA test with genotyping 9-24 months prior to Day 0
Positive HPV DNA test with genotyping at Day 0
Presence of an HPV-related cervical lesion within 5-24 months prior to Day 0. This lesion will be defined alternatively as:
6 more inclusion criteria and the exclusion criteria are on the listing.
This interventional, single-center, open-label randomized clinical study evaluates the efficacy of an oral dietary supplement (Pervistop®) in women with persistent Human Papillomavirus (HPV) infection. The supplement is a combination of four natural molecules: Epigallocatechin gallate (EGCG), folic acid (FA), vitamin B12 (B12), and hyaluronic acid (HA).The primary objective is to describe the effect of this association on HPV DNA integration into the host genome by measuring the clearance rate of viral oncoproteins E6 and E7. The full summary is on the listing.
Where, as registered
No US site; Italy (1).
Not yet recruitingNCT06875791
Safety and Efficacy Trial of TV5M01 for Radiation-Induced Mucositis in Head and Neck Cancer Patients.
Phase 1 and 2
Fundacion Clinica Valle del Lili
About 40 people
Starts Dec 28, 2025 (estimated)
In plain words A Phase 1 and 2 study of green tea extract in people 18 to 60, run by Fundacion Clinica Valle del Lili. It plans to enroll about 40 people at 1 site, none in the US.
Who it lists and where
Who the trial lists, as registered
Lists people 18 to 60. Conditions: Squamous Cell Carcinoma of the Head and Neck; Oral Mucositis.
What it tests, as registered
Green Tea Extract with Morphine; Active Comparator: Triple Mixture Oral Rinse for Radiation-Induced Mucositis
Registered summary
This study is a Phase 2, double-blind, randomized controlled trial evaluating the safety and efficacy of TV5M01 (a 5% green tea and 0.1% morphine gel) compared to triple mixture (0.19% lidocaine, 0.29% nystatin, and 5.50% hydroxides) for treating radiation-induced oral mucositis in patients with head and neck squamous cell carcinoma. The trial will enroll 40 patients (20 per group) with stage III-IV head and neck cancer receiving radiotherapy who develop grade 1 or higher mucositis. Participants will apply the assigned mouthwash three times daily from mucositis diagnosis until resolution. The full summary is on the listing.