D-mannose trials recruiting now

1 registration that name D-mannose as a study arm and are recruiting or about to, as ClinicalTrials.gov listed them on Oct 20, 2026. Read each listing for its full criteria and current status.

Kymata never assesses eligibility. Each listing names its own criteria; only its study team can say whether someone can join. Trial doses are given under the trial's monitoring and are not a schedule for anyone outside it.

Filter 1 registration

Status

1US sites across 1 state

All 1 registrations

RecruitingNCT06940622

A Trial of D-mannose for the Prophylaxis of Recurrent Urinary Tract Infections

  • No phase
  • University of Texas Southwestern Medical Center
  • About 90 people
  • Started Aug 1, 2025

In plain words A study of D-mannose in female participants 55 to 85, run by University of Texas Southwestern Medical Center. It plans to enroll about 90 people at 1 US site.

Who it lists and where

Who the trial lists, as registered

Lists female participants 55 to 85. Conditions: Recurrent UTIs; Recurrent Urinary Tract Infections; Recurrent Urinary Tract Infections in Women; Recurrent Urinary Tract Infection; Cystitis Recurrent; Cystitis Chronic; UTI; UTI - Urinary Tract Infection; UTI - Lower Urinary Tract Infection.

  • Female, post-menopausal, age ≥ 55 years old
  • Diagnosis of recurrent UTI, defined as ≥ 3 symptomatic culture-proven UTI episodes in 12 months or ≥ 2 in 6 months.
  • Currently free from a UTI determined based on absence of symptoms as determined by the UTI symptom assessment questionnaire79 and negative urine culture (<103 colony forming units per ml of urine).
  • Able to attend all follow-up appointments for the study.

1 more inclusion criterion and the exclusion criteria are on the listing.

What it tests, as registered

D-Mannose; Placebo

Registered summary

A randomized, double-blind, placebo-controlled, 12-month study to determine the effectiveness of D-mannose (2g daily) supplementation in rUTI (recurrent urinary tract infection) prevention in post-menopausal women.

Where, as registered

1 US site in 1 state.

ClinicalTrials.gov lists 5 open registrations for this search, including ones where D-mannose is not a study arm or that are past the 1 we keep. Search them on ClinicalTrials.gov (opens in new tab).

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