Chitosan trials recruiting now

7 registrations that name chitosan as a study arm and are recruiting or about to, as ClinicalTrials.gov listed them on Oct 20, 2026. Read each listing for its full criteria and current status.

Kymata never assesses eligibility. Each listing names its own criteria; only its study team can say whether someone can join. Trial doses are given under the trial's monitoring and are not a schedule for anyone outside it.

Filter 7 registrations

Status

Phase

All 7 registrations

RecruitingNCT07771127

HEMOSTATİC PAD AND SANDBAG

  • No phase
  • Uludag University
  • About 480 people
  • Started Jun 10, 2026

In plain words A study of chitosan in people 18 and older, run by Uludag University. It plans to enroll about 480 people at 1 site, none in the US.

Who it lists and where

Who the trial lists, as registered

Lists people 18 and older. Conditions: Coronary Artery Disease; Coronary Angiography; Vascular Access Site Complications.

  • Patients aged 18 years and older scheduled for femoral coronary angiography (CAG) and/or percutaneous coronary intervention (PCI)
  • Patients undergoing a single femoral arterial access procedure
  • Patients with sheath size typically 5-Fr, 6-Fr, or 7-Fr
  • Patients who are conscious, alert, and able to communicate

1 more inclusion criterion and the exclusion criteria are on the listing.

What it tests, as registered

Chitosan-Based Hemostatic Pad; Sandbag Application

Registered summary

The aim of this study is to compare bleeding outcomes, pain, comfort levels, sleep quality, and associated factors among patients receiving a chitosan-based hemostatic pad versus a sandbag following femoral coronary angiography (CAG) and percutaneous coronary intervention (PCI). Femoral coronary angiography (CAG) and percutaneous coronary intervention (PCI) are widely performed procedures for the diagnosis and treatment of coronary artery disease (CAD), which remains the leading cause of mortality worldwide (Batmaz \& Cengiz, 2023; Wardiyana et al., 2024). The full summary is on the listing.

Where, as registered

No US site; Turkey (Türkiye) (1).

RecruitingNCT07048028

Chitosan Irrigation in Premolar Root Canal Therapy (Randomized Trial)

  • No phase
  • ESRA DAĞCI
  • About 90 people
  • Started May 5, 2025

In plain words A study of chitosan in people 18 and older, run by ESRA DAĞCI. It plans to enroll about 90 people at 1 site, none in the US.

Who it lists and where

Who the trial lists, as registered

Lists people 18 and older; healthy volunteers accepted. Conditions: Apical Periodontitis; Dental Pulp Necrosis; Root Canal Infection.

  • Patients who agreed to participate in the study
  • Systemically healthy patient
  • Mandibular premolar teeth
  • Teeth that respond negatively to thermal tests and EPT

1 more inclusion criterion and the exclusion criteria are on the listing.

What it tests, as registered

Chitosan Low Molecular Weight (20-200 Mpa.S); Sodium Hypochlorite; EDTA chelating agents

Registered summary

The goal of this clinical trial is to learn which of three common root-canal rinsing (irrigation) methods removes bacteria most effectively in adult patients who need root-canal treatment. The main questions it will answer are: How much does a chitosan solution used alone lower the number of bacteria inside the root canal? Do the combinations sodium hypochlorite + chitosan or sodium hypochlorite + EDTA lower bacteria even more than chitosan alone? Researchers will compare the three irrigation methods to see which one achieves the greatest bacterial reduction. The full summary is on the listing.

Where, as registered

No US site; Turkey (Türkiye) (1).

RecruitingNCT06714695

A Crossover Clinical Study to Evaluate the Effect of Chitosan Mouthwash on Recurrence of Black Stains in Pediatric Patients

  • No phase
  • Al-Azhar University
  • About 17 people
  • Started Nov 1, 2024

In plain words A study of chitosan in people 6 to 12, run by Al-Azhar University. It plans to enroll about 17 people at 1 site, none in the US.

Who it lists and where

Who the trial lists, as registered

Lists people 6 to 12; healthy volunteers accepted. Conditions: Black Stains.

  • 1\. Cooperative child to be able to perform and tolerate different oral hygiene procedures 2. Parents providing informed consent 3. Accept 18 weeks follow up period 4. Teeth showing black stains without calculus.

The exclusion criteria are on the listing.

What it tests, as registered

Chitosan

Registered summary

The goal of this clinical trial is to learn if Chitosan mouthwash works to affect the recurrence of black stains in pediatric patients. The main questions it aims to answer are: Does Chitosan mouthwash lower the number of times participants need to do a scaling and polishing cleaning sessions more than normal? Does Chitosan mouthwash will decrease the recurrence of black stains in children and improve esthetics ? Participants will: Take chitosan every day for 4 months Visit the clinic once every 6 weeks for checkups and data collection

Where, as registered

No US site; Egypt (1).

Not yet recruitingNCT07544004

Chitosan Phonophoresis With Recurrent Hamstring Strain in Athletes

  • No phase
  • Cairo University
  • About 80 people
  • Starts Jul 1, 2026 (estimated)

In plain words A study of chitosan in male participants 18 to 35, run by Cairo University. It plans to enroll about 80 people at 1 site, none in the US.

Who it lists and where

Who the trial lists, as registered

Lists male participants 18 to 35; healthy volunteers accepted. Conditions: Hamstring Injury.

  • Male recreational football players who participate in non-professional football training or matches for at least two sessions per week (each session ≥ 45 minutes) for at least the previous 12 months
  • Aged 18-35 years
  • Clinically diagnosed with a new episode of acute unilateral recurrent hamstring strain. Recurrent injury is defined as a new acute hamstring injury in the same limb and muscle group (biceps femoris, semitendinosus, or semimembranosus) as…
  • Current injury onset within 3-10 days of enrollment.

4 more inclusion criteria and the exclusion criteria are on the listing.

What it tests, as registered

CHITOSAN PHONOPHORESIS; SHAM PHONOPHORESIS

Registered summary

The purpose of this randomized controlled trial is to evaluate and compare the effectiveness of adding chitosan phonophoresis as an adjunct to a rehabilitation-based exercise program compared to a rehabilitation-based exercise program with sham chitosan phonophoresis in athletes with recurrent hamstring strain injuries on the following outcomes: Hamstring-specific pain and function, Muscle strength and endurance, Lower extremity functions, Hamstring Flexibility symmetry and Hamstring injury healing score.

Where, as registered

No US site; Egypt (1).

Not yet recruitingNCT07084194

Impact of Integrating Two Nano Based Irrigants With Two Activation Techniques in Treatment of Teeth With Acute Pulpitis on Postoperative Pain and Flare up Incidence

  • No phase
  • Minia University
  • About 64 people
  • Starts Sep 10, 2025 (estimated)

In plain words A study of chitosan in people of any age, run by Minia University. It plans to enroll about 64 people and lists no sites yet.

Who it lists and where

Who the trial lists, as registered

Lists people of any age; healthy volunteers accepted. Conditions: Postoperative Pain; Flare up; Flare Up, Symptom.

  • Age 18-60 (adults only)
  • multiple-rooted with multiple root canal.
  • Permanent teeth with mature apex and complete root formation.
  • Without root caries.

6 more inclusion criteria and the exclusion criteria are on the listing.

What it tests, as registered

Chitosan Nanoparticles Irrigant; aloe vera nanoparticles irrigant; Diode Laser Activation; ultrasonic activator

Registered summary

This study aimed to evaluate and compare impact of integrating passive ultrasonic activation and laser activation with nano-chitosan and aloe vera in terms of postoperative pain and flare-up incidence in a randomized clinical trial.

Where, as registered

No sites listed yet.

Not yet recruitingNCT07482553

Antibiofilm Activity of Chitosan Nanoparticles Against Uropathogenic Escherichia Coli

  • Observational
  • Assiut University
  • About 60 people
  • Starts May 1, 2026 (estimated)

In plain words An observational study of chitosan in people 18 and older, run by Assiut University. It plans to enroll about 60 people at 1 site, none in the US.

Who it lists and where

Who the trial lists, as registered

Lists people 18 and older. Conditions: Urinary Tract Infections (UTIs); Catheter-Associated Urinary Tract Infections (CAUTIs); Biofilm Formation by Uropathogenic Escherichia Coli (UPEC).

  • 1\. Patients (inpatients or outpatients) clinically diagnosed with urinary tract infection (UTI).

The exclusion criteria are on the listing.

What it tests, as registered

chitosan nanoparticles

Registered summary

1. Isolation of uropathogenic Escherichia coli (UPEC) and determination of their Antimicrobial sensitivity Patterns. 2. Evaluation of biofilm-forming capacity of UPEC isolates. 3. Assessment of the antibiofilm efficacy of chitosan nanoparticles alone and in combination with ciprofloxacin against UPEC isolates. 4. Examination of the effectiveness of chitosan nanoparticle coating in preventing biofilm formation by UPEC on urinary catheter surfaces. 5. Evaluation of the impact of chitosan nanoparticles on the expression levels of biofilm associated genes in UPEC.

Where, as registered

No US site; Egypt (1).

Not yet recruitingNCT06755528

Effect of Shockwaves on Fallopian Tubes Adhesion

  • No phase
  • Cairo University
  • About 40 people
  • Starts Dec 30, 2024 (estimated)

In plain words A study of chitosan in female participants 25 to 35, run by Cairo University. It plans to enroll about 40 people and lists no sites yet.

Who it lists and where

Who the trial lists, as registered

Lists female participants 25 to 35. Conditions: Fallopian Tube Adhesion.

  • Their ages will be ranged from 25 to 35 years old.
  • Their body mass index (BMI) will be less than 35kg/m².
  • All women will be diagnosed with fallopian tubes adhesion by the physician.
  • They have regular menstrual cycles.

1 more inclusion criterion and the exclusion criteria are on the listing.

What it tests, as registered

Chitosan; shockwave therapy

Registered summary

The purpose of this study is to determine the effect of shock waves on fallopian tube adhesions.

Where, as registered

No sites listed yet.

ClinicalTrials.gov lists 36 open registrations for this search, including ones where chitosan is not a study arm or that are past the 7 we keep. Search them on ClinicalTrials.gov (opens in new tab).

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