4 registrations that name black seed as a study arm and are recruiting or about to, as ClinicalTrials.gov listed them on Oct 20, 2026. Read each listing for its full criteria and current status.
Kymata never assesses eligibility. Each listing names its own criteria; only its study team can say whether someone can join. Trial doses are given under the trial's monitoring and are not a schedule for anyone outside it.
Filter 4 registrations
Status
Phase
All 4 registrations
RecruitingNCT07525505
Nigella Sativa Oil for Eczematous Otitis Externa
No phase
Bezmialem Vakif University
About 85 people
Started Jan 12, 2026
In plain words A study of black seed in people 18 and older, run by Bezmialem Vakif University. It plans to enroll about 85 people at 1 site, none in the US.
Who it lists and where
Who the trial lists, as registered
Lists people 18 and older. Conditions: Eczema/Atopic Dermatitis; Otitis Externa.
Adult patients aged 18 years and older
Clinical diagnosis of eczematous otitis externa confirmed by otoscopic examination
Presence of at least one symptom related to the affected ear (itching, discomfort, otorrhea, or pain)
Willingness to participate and ability to provide written informed consent
The exclusion criteria are on the listing.
What it tests, as registered
Mometasone Furoate (MF); Nigella sativa oil
Registered summary
Eczematous otitis externa is a common inflammatory condition of the external auditory canal characterized by itching, discomfort, discharge, and pain. Topical corticosteroids are widely used for treatment; however, alternative therapies with fewer side effects are of increasing interest. This study aims to compare the efficacy of Nigella sativa (black seed) oil and mometasone furoate ear drops in the treatment of eczematous otitis externa. Nigella sativa is a natural product with known anti-inflammatory and antimicrobial properties. The full summary is on the listing.
Where, as registered
No US site; Turkey (Türkiye) (1).
Not yet recruitingNCT07494279
Efficacy of Nigella Sativa (Nisatol®) in Women With Borderline Blood Pressure Values or a Non-Dipper Blood Pressure Phenotype
No phase
Liaquat University of Medical & Health Sciences
About 106 people
Starts Mar 30, 2026 (estimated)
In plain words A study of black seed in female participants 18 to 65, run by Liaquat University of Medical & Health Sciences. It plans to enroll about 106 people at 1 site, none in the US.
Who it lists and where
Who the trial lists, as registered
Lists female participants 18 to 65. Conditions: Prehypertension; Hypertension.
Female participants
High-normal blood pressure values (≥130/85 mmHg) or mild hypertension (140/90 mmHg) with low cardiovascular risk and no current indication for pharmacological therapy
Presence of a non-dipper blood pressure phenotype on 24-hour ambulatory blood pressure monitoring
Absence of antihypertensive pharmacological treatment Exclusion Criteria
5 more inclusion criteria and the exclusion criteria are on the listing.
What it tests, as registered
Nigella sativa (Nisatol®); Placebo
Registered summary
This randomized placebo-controlled study evaluates the efficacy of Nigella sativa (Nisatol®) supplementation in women with borderline blood pressure values or a non-dipper blood pressure phenotype. The study aims to assess the effects of supplementation on blood pressure and resting heart rate in women presenting high-normal blood pressure values (≥130/85 mmHg) and/or a nocturnal non-dipper blood pressure pattern. Participants will be randomly assigned to receive either Nigella sativa (Nisatol®) or placebo for 12 weeks. The full summary is on the listing.
Where, as registered
No US site; Italy (1).
Not yet recruitingNCT07315555
Efficacy of Oral Nigella Sativa as Adjuvant Therapy in Children With Moderate Persistent Asthma
No phase
Tanta University
About 90 people
Starts Jan 1, 2026 (estimated)
In plain words A study of black seed in people 6 to 18, run by Tanta University. It plans to enroll about 90 people and lists no sites yet.
Who it lists and where
Who the trial lists, as registered
Lists people 6 to 18. Conditions: Community Acquired Pneumonia.
Children aged 6-18 years
Diagnosed with moderate persistent asthma according to the Global Initiative for Asthma (GINA) 2022 guidelines
Receiving stable standard controller therapy (inhaled corticosteroids ± long-acting β2-agonists) for at least 4 weeks prior to enrollment
Complementary and adjunctive therapies are increasingly being explored to enhance asthma control and reduce airway inflammation. Nigella sativa (black seed) is a medicinal plant used traditionally in multiple regions and has demonstrated anti-inflammatory, immunomodulatory, and bronchodilator effects. Its potential as an adjuvant therapy in asthma has attracted attention in both preclinical and clinical research
Where, as registered
No sites listed yet.
Not yet recruitingNCT06823544
A Comparative Single Blind Clinical Study on the Effect of Alvogyl, Eugenol, and Nigella Sativa (Black Seed Oil) for Alveolar Osteitis.
Phase 2
HITEC-Institute of Medical Sciences
About 40 people
Starts Feb 1, 2025 (estimated)
In plain words A Phase 2 study of black seed in people 16 to 70, run by HITEC-Institute of Medical Sciences. It plans to enroll about 40 people at 1 site, none in the US.
Who it lists and where
Who the trial lists, as registered
Lists people 16 to 70. Conditions: Alveolar Osteitis.
Patients over the age of 16, from both genders, who had their teeth extracted and were clinically diagnosed with dry socket.
Absence of systematic disease.
The exclusion criteria are on the listing.
What it tests, as registered
Alvogyl; Eugenol; Nigella Sativa Oil
Registered summary
Dry socket the unscientific term also known as alveolar or fibrinolytic osteitis is the most common postoperative complication following tooth extraction. Treatment of Alveolar osteitis can be either pharmacological on non-pharmacological. Management can be by irrigation, surgical intervention and placement of medicated dressing such as topical anti-bacterial, topical anesthetics and obtundants or combination of these three.this study aims to find the best and effective treatment for dry socket comparing Alveogyl, Eugenol and Black seed oil at this institution.