3 registrations that name apple pectin as a study arm and are recruiting or about to, as ClinicalTrials.gov listed them on Oct 20, 2026. Read each listing for its full criteria and current status.
Kymata never assesses eligibility. Each listing names its own criteria; only its study team can say whether someone can join. Trial doses are given under the trial's monitoring and are not a schedule for anyone outside it.
Filter 3 registrations
Status
All 3 registrations
RecruitingNCT06558526
Pectin Intervention Study and Long-term Follow-up in Lipid Transfer Proteins Allergic Patients
No phase
Fundación Pública Andaluza para la Investigación de Málaga en Biomedicina y Salud
About 62 people
Started Jan 13, 2025
In plain words A study of apple pectin in people 18 to 60, run by Fundación Pública Andaluza para la Investigación de Málaga en Biomedicina y Salud. It plans to enroll about 62 people at 1 site, none in the US.
Who it lists and where
Who the trial lists, as registered
Lists people 18 to 60. Conditions: Food Allergy.
Adults with a clear clinical history of food allergy after eating peach (oral allergy syndrome and/or systemic symptoms) and with or without clinical history of food allergy with peanut.
Sensitization to Pru p 3 by positive skin prick test (SPT wheal area >7 mm2) and specific IgE (sIgE >0.35 kUA/L)
Positive DBPCFC with peach juice.
If clinical history of food allergy with peanut, sensitization must be confirmed by positive SPT to peanut and sIgE >0.35 kUA/L to Ara h 9 and clinical reactivity through a positive DBPCFC with peanut.
1 more inclusion criterion and the exclusion criteria are on the listing.
What it tests, as registered
Apple pectin (DE 57%); Placebo
Registered summary
Pectins are dietary fibers that have shown a health effect on patients with food allergy, as they are capable of modifying the composition of gastrointestinal microbiota, and producing an immunomodulatory effect. Preliminary results by the investigators show that the intervention for 2 months with pectins produces an increase in tolerance to peach, and changes in the microbiota compared to the group of patients treated with placebo. In this project, the investigators aim to study these clinical effects and the involved mechanisms. The full summary is on the listing.
Where, as registered
No US site; Spain (1).
RecruitingNCT07093346
The Impact of Pectin Supplementation on Systematic Inflammation Pathway, Gut Microbiome, and Metabolic Health in Patients With Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD)
No phase
University of Nottingham
About 45 people
Started Jun 10, 2025
In plain words A study of apple pectin in people 18 and older, run by University of Nottingham. It plans to enroll about 45 people at 3 sites, none in the US.
Patients with clinical diagnosis of MASLD (formerly termed non-alcoholic fatty liver disease (NAFLD)), having assessment suggesting that liver fat > 5% (e.g.
Participants willing and able to give informed consent for participation in the study.
Participants aged ≥18 years who have a body mass index (BMI) between 18.5 and 39.9 kg/m2 and stable weight (weight gain or loss ≤ 3kg) for the past 3 months.
4 more inclusion criteria and the exclusion criteria are on the listing.
What it tests, as registered
Pectin; Cocoa Powder; Magnetic Resonance Imaging with Contrast
Registered summary
The goal of this clinical trial is to learn if daily supplementation with Low-methoxy (LM) pectin (polysaccharides extracted from citrus peels), which are commonly found in the UK diet (not pharmacological agents), can reduce systemic inflammation and improve gut microbiota composition in adults recently diagnosed with Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD). The full summary is on the listing.
Where, as registered
No US site; United Kingdom (3).
RecruitingNCT06955975
The Effect of Pectin Supplementation on Geriatric With Frailty: A Randomised Placebo-Controlled Dietary Intervention Study
No phase
University of Nottingham
About 30 people
Started Feb 10, 2025
In plain words A study of apple pectin in people 65 and older, run by University of Nottingham. It plans to enroll about 30 people at 1 site, none in the US.
Who it lists and where
Who the trial lists, as registered
Lists people 65 and older; healthy volunteers accepted. Conditions: Frailty at Older Adults; Pre-Frailty; Frailty; Diet; Dietary Fiber; Systemic Inflammatory Response.
Participant is willing and able to give informed consent for participation in the study.
Participant eligibility includes those aged >65 years who have a body mass index (BMI) between 18.5 and 39.9 kg/m2.
Participants who are considered as pre-frail or frail based on FRAIL (Simple Frailty Questionnaire).
The exclusion criteria are on the listing.
What it tests, as registered
Pectin; Whey protein
Registered summary
The study involves the intake of Low-methoxy (LM) pectin (polysaccharides extracted from citrus peels), which are commonly found in the UK diet (not pharmacological agents), to test their effects on systematic inflammation in the body and gut microbiome composition. The full summary is on the listing.