7 registrations that name apple Cider Vinegar as a study arm and are recruiting or about to, as ClinicalTrials.gov listed them on Oct 20, 2026. Read each listing for its full criteria and current status.
Kymata never assesses eligibility. Each listing names its own criteria; only its study team can say whether someone can join. Trial doses are given under the trial's monitoring and are not a schedule for anyone outside it.
Filter 7 registrations
Status
Phase
1US sites across 1 state
1
2 to 4
5 to 19
20 or more
All 7 registrations
RecruitingNCT07493226
Efficacy of Chemically Distinct Nonsteroidal Anti-Inflammatory Drugs (NSAIDs) and Pain Phenotypes in Adhesive Capsulitis
No phase
Konya Beyhekim Training and Research Hospital
About 120 people
Started Apr 1, 2026
In plain words A study of apple Cider Vinegar in people 18 to 75, run by Konya Beyhekim Training and Research Hospital. It plans to enroll about 120 people at 1 site, none in the US.
Who it lists and where
Who the trial lists, as registered
Lists people 18 to 75. Conditions: Frozen Shoulder; Adhesive Capsulitis; Shoulder Pain; NSAID (Non-Steroidal Anti-Inflammatory Drug); Nociplastic Pain; Neuropathic Pain.
Being between 18-75 years of age
Having shoulder pain that has lasted for at least one month and being diagnosed with primary frozen shoulder
Having a VAS pain level ≥ 4/10
Having ≥30 degrees of range of motion restriction in at least two planes (flexion, abduction, or external rotation)
1 more inclusion criterion and the exclusion criteria are on the listing.
Patients aged 18-75 years who present to a tertiary rehabilitation hospital with shoulder pain and restricted range of motion, and who consent to participate, will be included in the study. Eligibility will be determined based on predefined inclusion and exclusion criteria. Eligible patients will be randomly assigned to receive one of several nonsteroidal anti-inflammatory drugs (NSAIDs) with differing chemical properties (e.g., diclofenac, meloxicam, or indomethacin), in combination with a home-based exercise program for shoulder adhesive capsulitis. The full summary is on the listing.
Where, as registered
No US site; Turkey (Türkiye) (1).
RecruitingNCT06297967
Acetic Acid 2% Solution for Skin Ulcers
Phase 3
Consorci Sanitari de l'Alt Penedès i Garraf
About 104 people
Started Apr 27, 2025
In plain words A Phase 3 study of apple Cider Vinegar in people 18 and older, run by Consorci Sanitari de l'Alt Penedès i Garraf. It plans to enroll about 104 people at 1 site, none in the US.
Who it lists and where
Who the trial lists, as registered
Lists people 18 and older. Conditions: Ulcer, Skin.
Patients over 18 years of age.
Continued care (hospital or outpatient) in one of the Consorci Sanitari Alt Penedes i Garraf (CSAPG) units.
Presence of a cutaneous ulcer with biofilm, with an area of less than 120 cm2, and in any location (except the facial region).
Plan to undergo treatment and follow-up of the lesion (at least 8 weeks) at the study center.
2 more inclusion criteria and the exclusion criteria are on the listing.
What it tests, as registered
Acetic Acid; Prontosan
Registered summary
The objective of this clinical trial is to assess the effectiveness of acetic acid in patients suffering from chronic cutaneous ulcers with biofilm. The primary question it seeks to address is whether acetic acid (as a 2% topical solution) is superior to the current standard treatment for chronic cutaneous ulcers with biofilm at our center (Prontosan®). Participants will be randomly assigned to receive either the acetic acid solution treatment or the standard current treatment.
Where, as registered
No US site; Spain (1).
RecruitingNCT07549373
Effect of Diode Laser, Gudmar and Vinegar in Diabetic Patients During Root Canal Treatment
No phase
Sharda University
About 90 people
Starts May 1, 2026 (estimated)
In plain words A study of apple Cider Vinegar in people 25 to 60, run by Sharda University. It plans to enroll about 90 people at 1 site, none in the US.
Who it lists and where
Who the trial lists, as registered
Lists people 25 to 60. Conditions: Diabete Type 2.
Using radiographs, intraoral periapical radiographs (RVG) primary endodontic infection will be selected.
Multirooted teeth , root with periapical lesion will be selected
Type 2 diabetics between the ages of 25 years and 60 years will be chosen; both male and female patients
A fasting blood sugar level of 126 mg/dl and a random blood sugar level of less than 200 mg/dl
1 more inclusion criterion and the exclusion criteria are on the listing.
What it tests, as registered
940 nm diode laser; apple cider vinegar; Gymnema Sylvestre; Saline (NaCl); Diode laser and Gymnema Sylvestre; Diode laser and apple cider vinegar
Registered summary
Methodology Patient with diabetes 2 with informed consent -convenience sampling over a one year period.The tooth isolated with a rubber dam and the correct disinfection procedures will be used. researcher will do the Access preparation Working length -electronic apex locator (Dentsply Propex II) as well as a radiographic approach. After the canals will be obturated using ZOE sealer and gutta percha and post endodontic restoration is done using composite restoration. The full summary is on the listing.
Where, as registered
No US site; India (1).
RecruitingNCT05802121
Akkermansia Muciniphilia and Metabolic Side Effects of ADT
Early phase 1
Western University
About 30 people
Started Jul 2, 2025
In plain words An early phase 1 study of apple Cider Vinegar in male participants 18 and older, run by Western University. It plans to enroll about 30 people at 1 site, none in the US.
Who it lists and where
Who the trial lists, as registered
Lists male participants 18 and older. Conditions: Prostate Cancer; Metabolic Syndrome; Obesity; Cardiovascular Morbidity; Bone Diseases; Hyperlipidemias; Diabetes.
Men ≥18 years of age with histologically-proven metastatic castration-sensitive prostate adenocarcinoma planned to receive ADT (TNM stage Tany, Nany, M1) (see Appendix I).
Must have baseline imaging with 1) CT of the abdomen, and pelvis and bone scan or 2) PSMA PET scan
Age less than 18
Primary neuroendocrine prostate cancer
7 more inclusion criteria and the exclusion criteria are on the listing.
What it tests, as registered
Apple Cider Vinegar
Registered summary
The overriding objectives of this study are: 1. Primary outcomes: 1. To confirm that administration of oral acetate increases the proportion of A. muciniphilia in the stool samples of patients with metastatic, castration-sensitive prostate cancer compared to a standard of care arm. 2. To confirm tolerability and assess for side effects of oral acetate supplementation. 2. Secondary outcomes: 1. To determine if increased counts of A. muciniphilia correlate with improved metabolic parameters and improved bone health.
Where, as registered
No US site; Canada (1).
RecruitingNCT07563985
Effect of Lemon Juice and Apple Cider Vinegar on Postprandial Blood Glucose and Satiety in Healthy Individuals
No phase
Alanya Alaaddin Keykubat University
About 15 people
Starts May 1, 2026 (estimated)
In plain words A study of apple Cider Vinegar in people 18 to 35, run by Alanya Alaaddin Keykubat University. It plans to enroll about 15 people at 1 site, none in the US.
Who it lists and where
Who the trial lists, as registered
Lists people 18 to 35; healthy volunteers accepted. Conditions: Satiety; Postprandial Glycemia.
Healthy male and female volunteers aged 18-35 years
Body Mass Index (BMI) between 18.5 and 25.0 kg/m²
Willingness to provide written informed consent
Ability to comply with study procedures and fasting requirements
1 more inclusion criterion and the exclusion criteria are on the listing.
What it tests, as registered
Control (Water + White Bread); Lemon Juice 50 g; Lemon Juice 100 g; Apple Cider Vinegar 10 g; Apple Cider Vinegar 20 g
Registered summary
This clinical study aims to examine how acidic drinks (lemon juice and apple cider vinegar) affect blood sugar when consumed with a starchy food. The study focuses on healthy individuals and aims to understand whether these drinks can slow the rise in blood sugar after meals and affect feelings of fullness. The full summary is on the listing.
Where, as registered
No US site; Turkey (Türkiye) (1).
Not yet recruitingNCT07389226
The Effect of Apple Cider Vinegar Supplementation on 24-hour Urine Chemistry in Adults
No phase
University of Chicago
About 30 people
Starts Dec 2026 (estimated)
In plain words A study of apple Cider Vinegar in people 18 and older, run by University of Chicago. It plans to enroll about 30 people at 1 US site.
Who it lists and where
Who the trial lists, as registered
Lists people 18 and older; healthy volunteers accepted. Conditions: Kidney Stones; Urine Specimen Collection.
Controls: Adults above the age of 18.
Kidney stone patients: Adults above the age of 18.
History of majority (>50%) calcium oxalate kidney stones
The exclusion criteria are on the listing.
What it tests, as registered
Apple Cider Vinegar
Registered summary
This is a single-center prospective cohort study to evaluate the effect of short-term daily apple cider vinegar (ACV) supplementation on urine chemistry.
Where, as registered
1 US site in 1 state.
Not yet recruitingNCT07835425
Acetic Acid Ear Drops Versus 0.3 % Ciprofloxacin for Chronic Suppurative Otitis Media.
No phase
Dow University of Health Sciences
About 146 people
Starts Sep 23, 2026 (estimated)
In plain words A study of apple Cider Vinegar in people 18 to 70, run by Dow University of Health Sciences. It plans to enroll about 146 people at 1 site, none in the US.
Who it lists and where
Who the trial lists, as registered
Lists people 18 to 70. Conditions: Otitis Media Chronic.
Age 18-70 years
Either sex
Persistent, non-foul-smelling ear discharge for ≥3 months
Tubotympanic type chronic suppurative otitis media
1 more inclusion criterion and the exclusion criteria are on the listing.
This randomized controlled trial aims to compare the effectiveness of 2% acetic acid ear drops with 0.3% ciprofloxacin ear drops in the medical management of chronic suppurative otitis media (CSOM). The study will be conducted among adults aged 18 to 70 years attending the Otorhinolaryngology Department of Dr. Ruth K.M. Pfau Civil Hospital, Karachi. Participants will be randomly allocated to receive either 2% acetic acid or 0.3% ciprofloxacin ear drops three times daily for one month. The full summary is on the listing.
Where, as registered
No US site; Pakistan (1).
ClinicalTrials.gov lists 47 open registrations for this search, including ones where apple Cider Vinegar is not a study arm or that are past the 7 we keep. Search them on ClinicalTrials.gov (opens in new tab).